DISEASES OF THE LIVER AND SPLEEN. 103 



ternal organs of the dog. In each case the animal was aged 

 and in a hopeless condition when first seen by Messrs. Gowing, 

 consequently no treatment was attempted. 



''^Post-mortem examination was made soon after death, and 

 the appearances satisfactorily explained the condition of the 

 dogs during life. 



"In the first case which was examined in the beginning of 

 October, there was a large nodulated tumor, of a pale greyish- 

 yellow color at the root of the mesentery. Numerous depos- 

 its 'of a similar character were found all over the liver, both 

 covering the surface and extending to the interior of the gland. 



" Under the microscope the deposit was found to consist of 

 cells of various forms, caudate, spindle and fibre-cells, with 

 many others containing nuclei, and evidently multiplying by 

 the endogenous process. 



" A considerable quantity of fine fibrous stroma gave to 

 the deposit a density and hardness characteristic of scirrhous 

 growths. There was scarcely a trace of the milky juice which 

 is an invariable constituent of encephaloid tumor. 



" The second animal presented appearances in some re- 

 spects more marked than those which have just been de- 

 scribed. The subject of the disease was a Maltese dog, aged 

 fourteen years, which was seen by Messrs. Gowing only a few 

 hours before its death. 



"On post-mortem examination the liver was found to be 

 covered with yellowish spots, and a tumor of similar character 

 was detected in the spleen. 



" Microscopic examination of the morbid deposit resulted 

 in the detection of the same elements which had been observed 

 in the former case. 



" No history was obtained in either instance, but there can 

 be no doubt that the primary deposit occurred in the mesen- 

 tery in the first case, and in the spleen in the second, and that 

 it was followed in both by cancerous infiltration into the 

 structure of the liver." 



