290 THK MANAGEMENT AND DISEASES OF THE DOG. 



the muscles of the back. In the abdominal muscles attached 

 - to the spine, as well as in the peritoneum, there were also a 

 few isolated patches, generally running into each other in an 

 irregular manner. In the connective tissue of this region 

 were many marked haemorrhagic patches, and they were all 

 related more or less to others in the connective tissue sur- 

 rounding the left kidne}'. This organ exhibited on the infero- 

 external portion, which was in contact with the lumbar region, 

 a circular, eroded, hemorrhagic spot, about the size of a 

 rather large pea. The liver was reddish-brown in color, and 

 very much enlarged and indurated. The spleen was also en- 

 ,larged, very full of blood, and its parenchyma softened. The 

 heart was softened, and its texture very light colored'. , The 

 lungs were healthy, laut the stomach and intestines were some- 

 what swollen ; the stomach was empty, and the small intes- 

 tines nearly so ; the large- intestines contained a quantity of 

 fluid faces, but no scybala. The right lumbar region was 

 normal, and the right kidney large and light-colored. The 

 bladder contained a small quantity of muddy urine. 



" A colleague of Dr. Letzerich made a most careful and 

 interesting histological examination of the body, and found 

 at the seat of inoculation, in the wedge-shaped exudate formed 

 at the punctures and wounds, bacteria and plasma-globules 

 (^plasma-kugelri) closely agglomerated, the latter being in a 

 ■ finely granular condition. In a prepared section of the skin 

 it was noted that the sheaths of the hair in various parts were 

 full of bacteria, micrococci vesicles, and plasma-globules. In 

 the texture of the skin itself were numerous masses of bac- 

 teria and plasma-globules, as well as clusters of micrococci. 

 In the vicinity of those muscles which were stained by heemorr- 

 hagic patches, the capillaries were distended, and contained 

 the same abnormal elements ; these were also seen in the 

 connective tissue of these parts, as well as between the nerve- 

 bundles and muscular fibres. In the interior of the capil- 

 laries of the haemorrhagic patches themselves, between the 



