GENERAL DISEASES. 



291 



masses of red blood-globules, were immense colonies of 

 micrococci; the same condition was observed in the perito- 

 neum and its connective issue. The muscular fibrillas were 

 scarcely distinguishable in these patches, and their meshes 

 were enormously distended by escaped red blood-globules and 

 an extraordinary number of colonies of micrococci, with an 

 exuberance of plasma-globules. 



" In the round hasmorrhagic spot on the left kidney, and for 

 some depth in its substance, were masses of red blood-globules 

 and clustering rows of wandering micrococci. All the tu- 

 bules of the gland were filled with exudate, in which bacteria 

 and piasma-globules were seen in great quantities. In the 

 right kidney the migratory vegetable organisms (wandering 

 pilzm) were observed to be in their first stage of develop- 

 ment. Not a part of the liver that was examined, but con- 

 tained the retrograde vegetable formations ; all the cells were 

 filled with them. Between the fibres of the heart were only 

 discovered layers of plasma-globules and bacteria ; but many 

 of the smaller veins were filled with colonies of micrococci 

 which adhered to their walls. The spleen was in the same 

 condition as the liver ; indeed, the reporter states that it was 

 only an emulsion of cells, cell-debris {irummerti), nuclei, 

 bacteria, small micrococci, and a diversity of large plasma- 

 globules. The pulmonary bloodvessels contained the charac- 

 teristic diphtheria organisms {diphtheriepihes) ; in one portion 

 of the parenchyma of the lungs was found a small micrococci 

 ecchymosis. 



"All these alterations are well illustrated by colored 

 drawings. 



" From' the case of accidental transmission of diphtheria 

 through vaccination, and this experimental conveyance of the 

 malady to a dog, Letzerich draws the following conclusions : 

 I. Vaccine matter which has passed through a diphtheritic 

 subject, and become tainted, will not produce a vaccine pus- 

 tule at the place where it was inserted. 2. That lymph so 

 tainted, when introduced by inoculation, speedily gives rise 



