XIV CONTENTS. 



CHAPTER XVI. 

 Diphtheria. 



PAGE 



Historical — General facts — Bacillus diphtherise — Microscopical characters — 

 Distribution — Cultivation — Inoculation experiments — • The toxins of 

 diphtheria — Variations in virulence of bacilli ^ Summary of pathogenic 

 action — Methods of diagnosis 356 



CHAPTER XVII. 



Tetanus. 



Introductory — Historical ■ — Bacillus tetani — Isolation of tetanus bacillus — 

 Characters of cultures — Conditions of growth — Pathogenic effects — 

 Experimental inoculation — Tetanus toxins — Antitetanic serum — Methods 

 of examination — Malignant oedema — Characters of bacillus — Methods 

 of diagnosis — Bacillus botulinus — Quarter-evil — Bacillus aerogenes 

 capsulatus — Cultural characters ........ 376 



CHAPTER XVIII. 

 Cholera. 



Introductory — The cholera spirillum — Distribution of the spirilla — Cultivation 



— Powers of resistance^ — Experimental inoculation — Toxins of cholera 

 spirillum — Inoculation of human subject — Immunity — Modes of dis- 

 tinguishing the spirillum — General summary — Spirilla resembling the 

 cholera organism — Methods of diagnosis — Metchnikoff 's spirillum — 

 Kinkier and Prior's spirillum — Deneke's spirillum ..... 407 



CHAPTER XIX. 



Influenza, Plague, Relapsing Fever, Malta Fever, 

 Yellow Fever. 



Influenza bacillus — Microscopical ' characters ■ — Cultivation — Distribution — 

 Experimental inoculation — Methods of examination — Bacillus of plague 



— Microscopical characters — Cultivation — Anatomical changes produced 

 and distribution of bacilli — Experimental inoculation ■ — Paths and mode 

 of infection — Immunity — Relapsing fever — Characters of the spirillum 

 ■ — Relations to the disease — Malta fever — Micrococcus melitensis — 

 Relations to the disease — Methods of diagnosis — Yellow fever — Bacteria 



in yellow fever — The mosquito theory of infection 430 



CHAPTER XX. 



Immunity. 



Introductory — Acquired immunity — Artificial immunity . — Varieties — Active 

 immunity — Methods of production — Attenuation and exaltation of viru- 

 lence — Passive immunity — Action of the serUm — Antitoxic serum — 

 Standardising of toxins and of anti-sera — Nature of antitoxic action — 



