324 SWINE PRACTICE 



is destruction of the eye, and if both eyes are involved the animal 

 becomes blind and usually has to be destroyed. 



Neerobacillosis as a sequel of castration has been previously dis- 

 cussed. 



Necrobacillosis is a disease that may affect practically any and all 

 tissues of swine and is of considerable economic importance. The 

 most common forms of the disease are necrotic stomatitis and enteritis, 

 and necrosis of the sheath. 



Paratyphoid Infection 



Paratyphoid bacilli, particularly the one designated as paratyphoid 

 B., has been isolated from a disease condition in swine. In some cases 

 this bacillus was obtained in pure cultures direct from the lesions of 

 swine that were in the advanced stages of disease when destroyed for 

 autopsy purposes. 



This infection occurs primarily in swine in feed lots, particularly 

 when the lots are overstocked and are in an insanitary condition. 

 The disease in which the paratyphoid B. is associated may be acute 

 or sub-acute and the affection has been observed in feeder swine that 

 had been simultaneously immunized a month or six weeks prior to the 

 outbreak. 



The lesions noted on autopsy in these cases consisted of a marked 

 enlargement of the spleen and an enteritis. There may also be tume- 

 faction and infiltration of the lymph-glands. In some of these cases 

 there was also observed a blue or purple discolorization of the skin on 

 the ventral surface of the abdomen. Very limited hemorrhages were 

 observed in the mesenteric lymph-glands in one or two cases. The 

 blood is usually dark in color and does not coagulate readily. 



The first evidence of the disease is usually inappetence or diminished 

 appetite, the affected animal appearing depressed and having little 

 tendency to move. There is constipation at the onset, but it is usually 

 succeeded by diarrhea. There is rise of temperature and there may be 

 congestion of the skin. In the acute type of the disease the affected 

 animals usually die within two days after the onset. In the siibacute 

 or chronic form the affected animals may linger for several days and 

 may ultimately recover, although they are apparently permanently 

 damaged. The swine in the subacute type rapidly emaciate and be- 

 come weakened. 



The field diagnosis of this condition is difficult and the positive 



