FOUL-—BROOD. 447 
larger and the smaller (British Bee-Journal), but are they 
equally to be feared? 
These imperceptible ‘‘sticks’’ break successively into 
several parts, every one of which forms a colony of spores, 
that pass through divers shapes before developing into new 
bacilli. We can judge of the promptness of their repro- 
duction, and of their minuteness, when we read in Cheshire, 
that a dead larva frequently contains as many as one billion 
of these spores (28). 
788. In the Bulletin Agricole du Département de lV’ Aube, 
Mr. Brunet narrates the experiments made by Mr. Marcel 
Dupont, to breed the bacilli of foul-brood. Knowing that 
Pasteur used beef-broth in this kind of experiments, Mr. 
Dupont filled three glass-tubes with unsalted beef-broth, pre- 
pared according to the directions given by Pasteur, and after 
sealing and boiling them, to kill any living organisms that 
might have existed inside, he introduced into two of them, 
with a fine needle, a small quantity of a liquid, in which 
particles from the body of a diseased larva had been dis- 
solved. One week after, the broth in both of these tubes, 
was cloudy and full of bacilli, while the liquid, in the third 
tube, had remained clear and unchanged. 
789. Descrierion. As we have never seen a case of 
bacillus alvei, we will borrow from those who have been more 
‘‘lucky’’ (?) than ourselves, a description of the disease, 
for its detection in hives, and the remedies recommended 
by the best authorities. 
“In most cases the larva is attacked when nearly ready to seal 
up. It turns slightly yellow, or grayish spots appear on it. It 
then seems to soften, settles down in the bottom of the cell, in a 
shapeless mass, at first white, yellow, or grayish in color, soon 
changing to brown. At this stage it becomes glutinous and ropy; 
then, after a varying length of time, owing to the weather, it 
dries up into a dark coffee-colored mass. Usually the bees make 
noattempt to clean out the infected cells, and they will sometimes 
