152 CANINE MEDICINE AND SURGERY 



absorbed into the system because of imperfect 

 elimination and perverted metabolism. Thus we 

 have to deal not only with the toxemia produced 

 by the primary invading organism, but also with 

 the condition known as autointoxication or autj- 

 toxemia. 



Elimination may be secured by medicines caus- 

 ing free evacuations of the bowels and by those 

 stimulating the free excretion of urine. To obtain 

 the former, a dose of calomel should be given, 

 preferably in repeated small doses to effect; the 

 latter may be attained by appropriate doses of such 

 diuretic medicines as spirits of nitrous ether, potas- 

 sium nitrate, potassium acetate, or potassium 

 citrate. 



In addition to this cleaning-out process, the flora 

 of the alimentary tract must be kept under control 

 by the use of intestinal antiseptics, such as calcium 

 creosote, the sulphocarbolates of zinc, calcium, and 

 sodium advantageously combined with a bismuth 

 salt, acetozone, (fifteen grains to the quart of water 

 and given ad libitum in the drinking water), creo- 

 sote, or salol in enteric-coated pills or capsules. 



To raise the patient's powers of resistance a 

 bacterin composed of Bacillus bronchisepticus com- 

 bined with Staphylococcus, aureus and albus, must 

 be administered hypodermically every three days in 

 ascending doses. The action of the bacterin treat- 

 ment is much increased, especially if the patient 

 has not come under observation until the disease 

 is well advanced, if a simultaneous hypodermic in- 

 jection of nuclein is administered. The respiratory 

 complications must be treated as they arise, under 

 the directions given previously for handling respira- 

 tory diseases (see pp. 12-30). 



