I14 ELEMENTS OF APPLIED MICSOSCOPY. 
crease of white cells, accompanies all acute inflamma- 
tions as well as certain other conditions and may affect 
any one type of cells or all of them. In inflammations 
it is the polymorphonuclear neutrophiles which are 
increased; in trichinosis, on the other hand, the eosino- 
philes may reach 50% of the total. 
5. The Detection of the Malarial Parasite-—Blood ex- 
aminations are also undertaken for the diagnosis of 
malaria. The Protozdon malarial parasites gain entrance 
to the body from the bite of an infected mosquito in the 
form of minute spore-like bodies which penetrate the 
red corpuscles and there assume a crescentic form. Later 
the organism becomes amccboid, sends out blunt pseudo- 
podia, and develops nuclear granules. As it matures, it 
occupies the greater part of the red corpuscle and finally 
begins to divide, appearing in a rosette form, at last sepa- 
rating and discharging into the blood stream granules 
like those with which the cycle began. 
Blood may be examined in its fresh condition for the 
malarial parasite, but better preparations are obtained 
by staining. The Wright-Leishman method yields ad- 
mirable results, the cytoplasm of the parasite being 
stained blue and the nuclear granules a color varying from 
lilac through red to almost black. The general appear- 
ance of blood-cells containing the parasite of tertian 
malaria, Hemameba vivax, is indicated in the two upper 
fields of Fig. 45; the lower field shows a later flagellated 
stage in the flood stream. Only considerable experience 
in the examination of normal blood will enable the ob- 
server to recognize the invading organism with certainty. 
