THE BACILLUS OF TETANUS. 399 
toxin were then given the mare, so that it doubled its 
original strength in one month. The milk increased 
eightfold, but the foal’s continued to lose in antitoxin, 
although it was feeding on the antitoxic milk. 
Results of the Antitoxin Treatment in Tetanus. Tetanus 
is a comparatively rare disease both in man and animals, 
though in some localities it is more common than in 
others. In New York city there are usually fifteen 
to thirty cases following every fourth of July. Most of 
them are caused by infection through blank cartridge 
wounds. Recovery sometimes follows from the ordi- 
nary symptomatic treatment or without treatment at 
all, so that the statistics of cures of the disease by the 
injection of antitoxic serum must be very carefully 
sifted before they can be accepted as reliable. Lambert, 
however, who has recently made an exhaustive study 
of tetanus, states that in a total of 114 cases of this 
disease treated with antitoxin, according to published 
and unpublished reports, there was a mortality of 40.35 
per cent. Of these, 47 were acute cases—that is, cases 
with an incubation period of eight days or less and with 
rapid onset, or cases with a longer period of incubation, 
but intensely rapid onset of symptoms; of these the 
mortality was 74.46 per cent. Of the chronic type— 
those with an incubation period of nine days or more, 
or those with shorter incubation with slow onset—there 
were 61 cases, with a mortality of 16.39 per cent. With 
a still larger number of cases the results indicate that 
with tetanus antitoxin about 20 per cent. better results 
are obtained than without. The new method of inject- 
ing from 3-16 ¢.c. of antitoxic serum into the lateral 
ventricles has not, in the writer’s opinion, shown itself 
to be superior to the intravenous or subcutaneous 
