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PRODUCERS OF ABSCESS, CELLULITIS, ETC. 469 
of the skin and mucous membranes—impetigo, sycosis, 
phlyctenular conjunctivitis; in purlent conjunctivitis 
and inflammation of the lachrymal sac; in acute ab- 
scesses formed in the lymphatic glands, the parotid 
gland, the tonsils, the mamma, etc.; in metastatic 
abscesses and purulent collections in the joints; in em- 
pyema; in infectious osteomyelitis, in ulcerative endo- 
carditis, pyelonephritis, etc. It is one of the chief | 
etiological factors in the production of pyzmia in the 
various pathological forms of that condition of disease. 
Not all persons are equally susceptible to infection 
by the staphylococcus; those who are in a cachectic 
condition or suffering from constitutional diseases, like 
diabetes, are especially predisposed to infection. In 
healthy individuals certain parts of the body, as the 
back of the neck and the seat, are more liable to be 
attacked than others, with the production of furuncles, 
-carbuncles, etc. In persons in whom sores are readily 
caused, in consequence of disturbances of nutrition, as 
in exhausting diseases, the micrococci settle at the points 
of least resistance. Such conditions are present in the 
bones of debilitated young children, in fractures, and 
injuries in general. 
The pyogenic properties of the staphylococcus have 
been demonstrated upon man by numerous experiments. 
Garré inoculated a small wound at the edge of one of 
his finger-nails with a minute quantity of a pure cul- 
ture, and purulent inflammation extending around the 
margin of the nail resulted from the inoculation. 
Staphylococcus aureus was recovered in cultures from 
the pus thus formed. The same observer applied a 
considerable quantity of a pure culture obtained from 
this pus—third generation—to the unbroken skin of 
