494 BACTERIOLOGY. 
tended honesty of his conclusions, it is my conviction 
that they give undoubtedly too favorable a view of the 
value of the serum. 
In the comparatively few cases of puerperal fever, 
wound infection, scarlet fever, and bronchopneumonia 
that we have seen under the treatment the apparent re- 
sults have not been uniform. Only occasionally did 
we see results which appeared to be distinctly due to 
the serum. 
In a number of cases of septicaemia where chills had 
oceurred daily for days they ceased absolutely or 
lessened under daily doses of 20 to 50 ¢.c. The 
temperature, though ceasing to rise to such high eleva- 
tions, did not average more than one or two degrees 
lower than before the injections. The serum treat- 
ment was kept up for four weeks. Some cases conva- 
lesced; others after a week or more grew worse and died. 
In some cases the temperature fell immediately upon 
giving the first injection of serum, and after subse- 
quent injections remained normal, and the cases seemed 
greatly benefited. Asa rule, in these cases no strep- 
tococci or any other organisms were obtained from the 
blood. On bronchopneumonia, laryngeal diphtheria, 
and in phthisis we have seen absolutely no effect. 
The results obtained here in New York by both 
physicians and surgeons have not, on the whole, been 
very encouraging. 
In some of the cases where apparently favorable re- 
sults were obtained other bacteria than streptococci were 
found to be the cause of the disease. We believe that 
the following conclusions will be found fairly accurate : 
A single antistreptococcic serum protects healthy 
rabbits from infection from most of the streptococci 
obtained from human sepsis due to the streptococcus, 
