MICROCOCCUS LANCEOLATUS. 515 
In all there was a decided fall of temperature in from 
six to twelve hours after subcutaneous injections of from 
4 to 6c.c. of the serum. The pulse and respirations 
were also diminished in frequency. In two cases the 
temperature fell to 37° C. Twice it fell and remained 
at normal. In other cases it fell only temporarily. 
The number of cases reported in which the blood- 
serum of animals artificially immunized against pneu- 
monic infection has been used for the treatment of the 
disease, although considerable, is still too few to warrant 
the expression of any definite opinion as to the final 
value of this as a therapeutic agent. In the cases we 
have observed there has been in some a slight imme- 
diate lowering of the temperature ; in others no ap- 
parent change. Asa rule, the cases did rather better 
than was expected, but certainly no striking curative 
effects were apparent. The cases did not develop 
pneumococcus blood infection, and it seems probable 
that the serum may be able to prevent a general infec- 
tion from taking place from the diseased lung, even 
though it may fail to influence the local process. It 
has also been shown that these injections of antipneu- 
motoxic serum are practically harmless. 
