534 BACTERIOLOGY. 
Brése, in 1893, stated that the culture medium is the 
only reliable agent for the detection of the gonococcus. 
This latter statement is certainly applicable to chronic 
urethritis of the male. Neisser, in 1893, stated that 
in chronic urethritis with slight discharge the examina- 
tion with a culture medium for gonococci will replace 
the cover-glass. 
