THE FUNGI. 619 
tion of the fungus are found to have disappeared, leav- 
ing only the remains of the club-like ends, thus showing 
that no growth has taken place. Ponfick, Johne, Rot- 
ter, Lining, and Hanan claim to have obtained positive 
results in animals, but according to Bostrom these re- 
sults are not conclusive. The animals used for experi- 
mentation have been calves, swine, dogs, rabbits, and 
guinea-pigs, the places of inoculation being the anterior 
chamber of the eye, the subcutaneous intercellular tissue, 
the peritoneum, and the blood; and the material em- 
ployed for inoculation, pus from the infected regions in 
animals and man; very rarely cultures. _ 
A number of other streptothrices have been described 
in connection with pathogenic processes, but most of 
them are not well defined. They have been found in 
brain abscess, cerebro-spinal meningitis, pneumonic 
areas, and in other pathological conditions. Eppinger 
injected cultures into guinea-pigs and rabbits, and ob- 
served that it caused a typical pseudotuberculosis. Con- 
solidation of portions of both lungs, thickening of the 
peritoneum, and scattered nodules resembling tubercles, 
were noted in a case of human infection as due to a 
streptothrix by Flexner, in which the pathological 
picture of the disease resembled so nearly tuberculosis 
in human beings that the two diseases could be sepa- 
rated only by the causative micro-organism in each case. 
THE FUNGI. 
Most of the fungi are not pathogenic and interest us 
merely as organisms which are apt to infect our bac- 
teriological media. Some are, however, true parasites, 
and already we know that ringworm, favus, thrush, and 
pityriasis versicolor are caused by fungi. Only those 
causing ringworm and favus can be touched on here. 
