632 : APPENDIX. 
ordinary rapidity. A flagellum may break off from 
the main body and move about independently among 
the corpuscles. While these flagellate bodies appear 
in both the tertian and quartan fevers they are very 
much more numerous in the irregular malaria. The 
significance of the flagellate form is still under discus- 
sion. By some it has been regarded as a degenerate 
form. 
In the estivo-autumnal, quotidian, or pernicious mala- 
rial fevers there is developed also a very striking body, 
to which much attention has been paid, viz., the ‘‘ cres- 
cent’? of Laveran. In any case of irregular malarial 
fever which has lasted a week or more these bodies are 
to be found. They are developed within the red blood- 
corpuscle, the margin of which may usually be seen on 
the concave surface of the crescent. The border is very 
sharply defined, the protoplasm uniform, homogenous, 
with coarse pigment granules, often in the form of rods, 
which are collected about the centre. Bodies similar 
in structure, but differing in form, being ovoid and 
rounded, are also met with; and the change of a cres- 
cent into an ovoid or rounded body can be traced, which, 
in turn, may in some instances be seen to project flageila 
or form a flagellated body similar to that derived from 
the extracorpuscular organisms above referred to. 
Most authors say that both kinds of flagellate bodies 
do not develop unless the blood be exposed to the air, 
but an exposure of one or two minutes gives the best 
results. It would seem that they do not exist as flagel- 
late forms in the circulation. (Osler, in Allbutt’s Sys- 
tem of Medicine.) 
Pigmented Leucocytes. Typical pigmented leucocytes 
are very characteristic signs in malarial blood, and on 
