RABIES. 669 
New York Health Department have been very en- 
couraging. 
Other methods of immunization against rabies have 
been proposed by different investigators. But all of 
these methods have proved on trial to be unsatisfactory 
and unreliable, beside being not devoid of danger. As 
early as 1889, Babes and Lepp conceived the idea that 
it might be possible by means of the blood to transmit 
conferred immunity from rabies from one animal to 
another; but although the success of these investigators 
was not great, Tizzoni and Schwartz, and later Tizzoni 
and Centanni, worked out a method of serum inocula- 
tion and protection in rabies which is worthy of atten- 
tion. In this method not the rabic poison itself but 
the protective material formed is injected into the 
tissues. These observers showed that the serum of 
inoculated animals is capable of destroying the patho- 
genic power of the rabic virus—not only when mixed 
with it before injection, but when injected simultane- 
ously or within twenty-four hours after the intro- 
duction of the virus into the body. This serum 
treatment of rabies is still in the experimental stage. 
We ourselves have had no experience with it, nor has 
it been adopted in Paris, or, so far as we know, in other 
places. It is quite possible that others will not obtain 
such good results as the authors of the treatment, or 
that it may not prove so efficacious in the treatment of 
man as it has been found to be in experimental work. 
The Cauterization of Wounds Infected with the Virus 
of Rabies after an Interval of Twenty-four Hours. It 
is commonly believed that unless a cautery is used 
within an hour after infection by a suspected animal it 
is useless to apply it. This belief is held by physi- 
