190 APPLIED BACTERIOLOGY 



seen in the urine, it is possible that the gonococcus is 

 present, and might produce gonorrhoea on coitus with a 

 healthy female. Wiirtz recommends that, before making 

 search for the organism in such filaments, an artificial 

 irritation should be excited by the injection of nitrate of 

 silver solution, so as to cause a more copious discharge of 

 pus, in which the gonococcus, if present, can be demon- 

 strated. This view has also been discussed favourably in 

 certain American journals, and a short article has appeared 

 on it in the Medical Press (November 20, 1895) . 



The gonococcus has also been found in cystitisi in 

 chronic urethritis, and in bubos, though the latter are 

 chiefly caused by streptococci. 



Practical Precautions. — The gonorrhoeal pus is infective 

 on any mucous surface, and if accidentally introduced into 

 the eye may cause its loss, unless treated within two days. 

 Patients should therefore be warned of this danger. 



GLANDERS. 



The bacillus of glanders was first described by Loffler and Sohutz — 

 Proof of its specificity — Morphology — Method of growth in culture — ■ 

 Attenuation occurs rapidly in culture — Susceptible animals — Farcy 

 — Diagnosis of glanders — Mallei'n — Preventive measures. 



The Bacillus mallei- was first described in the year 1882 

 by Loffler and Schutz, and was proved by them to be the 

 specific cause of the disease by the successful inoculation 

 of horses and asses with pure cultures of the bacillus. 



The organism is a short thick rod about 2 /i long by 

 0'5 /i thick; that is to say, it is somewhat shorter and 

 thicker than the tubercle bacillus. 



Growth on Media. — The bacillus grows on potato at blood- 

 heat, but only slightly at room - temperature ; it grows 

 slightly on gelatine, and readily on glycerine agar, but the 



