86 PRACTICE OF EQUINE MEDICINE. 



If mallein fails to give a reaction, what causes such 

 failure ? 



It is due either, to not being properly injected, the mallein 

 not being good, cases being well advanced, temperature too high 

 at time of injection, certain other conditions or diseases existing, 

 also when the bacilli are not multiplying or acting on the system. 



Does mallein have a curative action? 



In some cases it appears to have somewhat of a curative action. 

 At any rate the disease has been noticed to recede in some cases 

 after its use. 



MALADIB DU COIT. 



What are the synonyms? 



Dourine, equine syphilis, venereal disease, disease of coitus. 



Define dourine. 



This is a contagious venereal disease seen in stallions and 

 mares, rather chronic in its course, and characterized by a discharge 

 from the genital organs, associated with ulceration, and followed 

 by paralysis. 



What is the cause? 



It is produced by Trympanosoma Equiperdum, which gets 

 into the blood, semen, vaginal secretions, milk and erosions of the 

 mucous membrane of the genital organs. It is a disease seen after 

 copulation, and the vehicles of contagion are in the urethra of the 

 male and the vagina of the female. 



This disease was first noticed in 1796, and has since been seen 

 in Poland, Germany, Austria, Switzerland, England, Belgium, 

 and was imported into this country in 1880. 



How long is the period of incubation ? 



It varies from one to six or eight weeks. 



What are the symptoms seen in the female? 



A few weeks after copulation a discharge from the vulva is 

 noticed; it is clear at first, but soon becomes opaque, yellowish in 

 color, and sometimes ichorous. 



The genital organs become swollen, the mucous membrane 

 thrown in folds and covered with a gelatinous-like fluid ; red spots 

 or erosions on the mucous membrane may also be present. 



