VI CONTENTS 



Page. 



Pseudechis II 9 



DisHra I2 ° 



Hydrophis I21 



Enhydrina I21 



Hydrus I21 



Opisthoglyphous Colubridae I22 



XII. Effect of Snake Venom upon the Nervous System and Effect of the Sequelae 



upon the Respiratory and Circulatory Functions 124-132 



Crotalinae * 2 4 



Viperinae I2 9 



Elapinse * 2 ° 



Hydrophiinae I 3 I 



XIII. Effects of Snake Venom upon the Coagulability of the Blood I33 -I 4 2 



Anticoagulating Property of Snake Venoms *39 



XIV. Neurotoxins of Snake Venom I 43 _I SS 



Histological Changes Caused by Neurotoxins of Snake Venom 15° 



Venom-neurolysis in vitro I S° 



Cells of Sycotypus I S I 



Histological Changes of Nervous System Produced by Snake Venom . . 152 



XV. Haemorrhagins of Snake Venom 156-161 



Histological changes caused by Venom Haemorrhagins 161 



XVI. Venom-haemolysis and Venom-agglutination 162-198 



Effects in vivo and in vitro 162 



The New Era of the Study of Venom Haemolysis 169 



Mechanism of Venom Haemolysis *85 



Antihaemolytic Properties of Cholesterin T 94 



XVII. Cytolysins in Snake Venom 199-205 



Effect of Venom on Cells of Warm-blooded Animals 199 



Effect of Venom on Cells of Cold-blooded Animals 201 



Cytolytic Action of Snake Venom on Micro-organisms 2 °S 



XVIII. Histological Changes produced by Snake Venom on various Organs and 



Tissues 206-209 



Action of Snake Venom upon the Liver 2 o7 



Action of Snake Venom upon the Kidney 2 o8 



Action of Snake Venom upon the Lungs 208 



Action of Snake Venom upon the Spleen 208 



Action of Snake Venom upon the Heart 209 



Action of Snake Venom upon the Muscles 209 



XIX. Ferments in Snake Venom 210 



Proteolytic Action of Snake Venom 211-214 



Diastatic Actions of Snake Venom 213 



Lipolytic Action of Snake Venom 213 



XX. Antibactericidal Properties of Snake Venom 215-218 



XXI. Toxicity of the Tissues of Venomous Snakes 219 



XXII. Effects of Snake Venom on Mucous, Conjunctival, and Serous Membranes and 



Alimentary Tract 220-222 



XXIII. Artificial Immunization 223-232 



Active Immunity — Prophylactic Inoculation 223 



Passive Immunity — Antivenins 225 



XXIV. Specificity and Therapeutic Values of Antivenins 233-245 



Specificity of Antivenins as a whole 233 



Specificity of Antivenins due to differences in the characteristic toxic 



principles of the venom of each species 233 



Specificity of Antivenins due to differences in individual cytotropic toxins 



of the venoms of different species 236 



Crotalus adamanteus Antivenin 239 



Crotalus terrificus Antivenin 240 



Ancistrodon piscivorus Antivenin 240 



Lachesis Iwnceolatus Antivenin 240 



Lachesis fiavoviridis Antivenin 241 



Calmette's Antivenin 241 



Therapeutic Value of Antivenins 241 



XXV. Interactions between Venom and Antivenin 246-260 



Establishment of the Chemical Nature of Venom-antivenin Reaction .... 246 



Regeneration of Venom and Antivenin from their Neutral Combination .... 248 



