116 THE CELL DOCTRINE. 



tion,"* in 1867, that the observation attracted the 

 attention it deserved. Since then it has been con- 

 firmed again and again, and most conclusively lately 

 by Arnold, of Heidelberg. t 



The theory which grew out of Cohnheim's obser- 

 vation was, that it is the colorless corpuscle of the blood, 

 rather than the connective tissue corpuscle, which is 

 the starting-point of all new formations, healthy and 

 morbid. It is the accumulation of these corpuscles 

 outside of the bloodvessels, in the interspaces of the 

 fibrillar connective tissue, which forms the beadlike 

 rows of cells figured by Virchow and others. It is these 

 which, accumulated in larger numbers, forms the pus 

 of an abscess. It is these which, perverted in the 

 direction of their development, produce the tissu'e of 

 tubercle, cancer, sarcoma, and other forms of morbid 

 growth. It is these, also, which become the medium 

 of repair of all injured or destroyed tissues which are 

 capable of regeneration, whatever their complexity 

 or simplicity. 



That the colorless corpuscle plays a most important 

 role in the production of new formations, healthy 

 and morbid, few now deny ; but that it is the sole 

 morphological element, exclusive of the connective 

 tissue corpuscle, thus active, many will not admit. 

 Conspicuous among those who have combated this 

 exclusive view are Strieker and Norris,! whose ob- 



* Ueber Entziindung und Eiterung, Virchow's Archiv, Bd. xl, 

 1867, p. 1. 



f Ueber Diapedesis, Virchow's Archiv, vol. 58, 1873. 



% Versuohe iiber Hornhaut Entziindung, Studien aus dem In- 

 stitute fiir Experimentelle Pathologle in Wien, aus dem Jahre 

 1869. 



