THE CELL DOCTRINE. 117 



servations and experiments in the production of 

 inflammation in tlie cornefe of frogs and rabbits have 

 attracted much attention. Their object was to show 

 that the connective tissue corpuscles (the corneal cor- 

 puscles here) shared in the formation of the products 

 of inflammation by their proliferation, and that the 

 colorless corpuscles themselves, after their migration 

 beyond the walls of the bloodvessels, also underwent 

 cell division, and thus contributed in a second man- 

 ner to the formation of pus. They argued, also, that 

 the enormous accumulations pf pus in large abscesses 

 could not be reasonably accounted for on the ground 

 that the only source of the pus-corpuscle is the wan- 

 dered-out colorless corpuscle. 



These observations of Strieker and Norris are gen- 

 erally acknowledged as having settled the question 

 in favor of the view, that there are two elements of 

 organization, — the colorless corpuscle and the connec- 

 tive tissue corpuscle, either of which may also become 

 the starting-point of pathological new formations. 



NEW VIEWS ON THE STUUOTUEE OF CELLS AND 



NUCLEI.— 1877-78. 

 As early as 1867, C. Frommann* published a pam- 

 phlet on the "ISTormal and Pathological Anatomy of 

 the Spinal Cord," in which he states that the pres- 

 ence of fibrils in the nuclei and nucleoli of cells, first 

 observed in ganglion-cells, was demonstrated by him 

 also in the cells of connective tissue, cartilage, and 



* Untersuchungen fiber die normale und pathologische Anato- 

 mie des Bfickenmarks, 2 Theil. Jena, 4. Mit 6 Taf. p. 17. For 

 abstract of, see Henle and Meissner's Berioht fiber die Forschritte 

 der Anatomie und Physiologie, in Jahre 1867, Leipzig, 1868. 



