Inheritance of Acquired Characters 253 
protrusion of the eye on the same side, and further, that he 
had “also had many cases in which some of the progeny of 
parents thus affected have shown considerable protrusion 
of the eyeballs of both sidés, and this seemingly abnormal 
protrusion has occasionally been transmitted to the next gen- 
eration. Nevertheless, I am far from satisfied that this latter 
fact is anything more than an accidental coincidence.” This 
reservation is made on the ground that the protrusion in the 
young is never so great as in the parents, and also because 
there is amongst guinea-pigs a considerable amount of in- 
dividual variation in the degree of prominence of the eye- 
balls. Romanes, while unwilling to deny that an ‘“ obviously 
abnormal amount of protrusion, due to the operation, may be 
inherited in lesser degree,” is also unwilling to affirm so 
important a conclusion on the basis of these experiments 
alone. 
In regard to Brown-S€quard’s 6th statement, Romanes found 
after injury to the restiform body that hematoma and dry 
gangrene may supervene, either several weeks after the 
operation, or at any subsequent time, even many months 
afterward. The disease usually affects the upper parts of 
both ears, and may then gradually extend downward until 
nearly the whole ear is involved. “As regards the progeny 
of animals thus affected in some cases, but by no means in 
all, a similarly morbid state of the ears may arise apparently 
at any time in the life history of the individual. But I have 
observed that in cases where two or more individuals of the 
same litter develop this diseased condition, they usually do so 
at about the same time, even though this may be months after 
birth, and therefore after the animals are fully grown.” More- 
over, the morbid process never extends so far in the young as 
it does in the parents, and “it almost always affects the middle 
third of the ear.” Several of the progeny from this first gener- 
ation, which had apparently inherited the disease, but had not 
themselves been directly operated upon, showed a portion of 
