The Head and Neck iii 



not affect the health, except in the case of the bronchial glands where 

 they may give rise to impairment of cardiac and respiratory function 

 by compression of the intramediastinal vasculo-nervous structures. 



Symptoms and Diagnosis. To the touch they are smooth, hemis- 

 pherical lumps, firm, elastic, and painless. They are freely mobile 

 one on another in external glands and do not become adherent to 

 surrounding parts. 



Treatment. Where these growths appear as a blemish, they may 

 be .presented for treatment, when they will be found amenable to 

 arsenic administered internally. 



Mtdignant Ljrmphadenoma. Hodgkin's Disease. This is a 

 rase disease in which there is an extensive and progressive symmet- 

 rical enlargement of the glands throughout the system, including not 

 only external lymphoid tissue, but also that of the spleen, the kid- 

 aeys, the liver, and the bone marrow. In the human subject it is 

 most common in the young adult male, and this would also seem to 

 be true of the dog, as I have observed it in males of the age of two 

 or three years. The cause is unknown. 



Symptoms and Diagnosis. The enlargement develops progres- 

 sively in one gland after another until a whole cluster of glands is 

 implicated. Another group becomes likewise affected until all the 

 external glands are involved, and finally the internal lymphoid tissue. 

 The submaxillary glands are usually the first to show the change, 

 and at this stage are liable to be mistaken for goiter, then the cervi- 

 cal, then the axillary, and then the inguinal. The enlargements are 

 not painful and show no tendency to break down. They adhere 

 together forming lobulated masses, but do not form adhesions with 

 the surrounding tissues and remain freely mobile. This feature 

 serves to distinguish the condition from acute or chronic lympha- 

 denitis or lymphosarcoma. As the disease progresses the pulse be- 

 comes rapid and the appetite capricious. Lethargy develops, the ani- 

 mal showing disinclination to mount steps or to travel far. The ab- 

 domen , becomes abnormally distended and by careful palpation the 

 internal enlargements can be distinguished, particularly of the 

 spleen. 



Treatment. There is no treatment possible and the prognosis 

 must . always be unfavorable, a fatal termination ensuing in the 

 course, of one or two years. 



Lymphatic Leukemia. Leukemic Lymphadenama. This dis- 



