2IO Surgical Diseases and Surgery of the Dog 



was invariably followed by fatal results. In six animals (cats and 

 dogs) operated upon, death occurred within a few hours to nine 

 days, either from shock, profuse hemorrhage, or gangrene of a 

 portion of the duodenum, owing to that part of the bowel being 

 deprived of its mesenteric vascular supply over an area correspond- 

 ing to the attachment of the pancreas. 



Hedon and Mouret grafted portions of the pancreas sub- 

 cutaneously in a number of dogs in the following manner: Celio- 

 tomy was performed and the vertical portion separated from the 

 rest of the organ at the level of its junction with the head by means 

 of a ligature, without interfering with its vascular supply, it being 

 nourished by a special artery. This portion was then secured to 

 the subcutaneous tissue by sutures, its vascular pedicle passing 

 through the opening in the abdominal wall. In two or three days 

 after fixation a large retention-cyst formed through the persistent 

 secretion accumulating behind the ligature and distending the ducts. 

 A fistula resulted, but finally the secretion stopped and this por- 

 tion of the gland comported itself like a ductless gland. In three 

 weeks union was established with the subcutaneous tissue, and 

 newly-formed vessels sufficient for its nutrition had penetrated the 

 graft. The vascular pedicle was then suppressed and the graft 

 was complete, but the latter was found to undergo progressive 

 atrophy under the influence of connective tissue growth. In these 

 cases, if the abdominal portion of the gland remaining in situ 

 was extirpated, with a few exceptions no glycosuria developed 

 provided the grafted portion had not undergone advanced atrophy. 

 But if much atrophy was present there was considerable glycosuria. 

 The graft being extirpated, severe glycosuria appeared and termin- 

 ated the life of the animal. 



Senn found that if he left the organ intact but occluded the 

 excretory duct, which rendered the animal physiologically in the 

 same condition as after complete extirpation as far as intestinal 

 secretion was concerned, the health remained perfect for three or 

 four weeks, but death resulted from marasmus in two to four 

 months. From this it will be seen that removal of the pancreas 

 must not comprehend resection of more than a portion of the organ, 

 and that the duct should be left intact. 



Senn has shown that the operation is not dangerous provided 

 hemorrhage, arterial and venous, be controlled, though Vaughan 



