376 Surgical Diseases and Surgery of the Dog 



cessive granulomatous formation or true sarcoma. This form of 

 growth is referred to under Infective Granulomata. True sarcoma 

 of the Vagina does, however, sometimes occur, for myxomatous 

 growths have been observed to undergo sarcomatous transforma- 

 tion. 



The disease occasionally occurs as a general sarcomatous for- 

 mation (Megnin, Froehner). A variety known as myelogenic sar- 

 coma is sometimes seen attacking the interior of Bone Cavities, 

 principally of the fore-arm and the shoulder. The distinguishing 

 feature between myelogenic sarcoma and periosteal sarcoma is that 

 the former is an excessive development of the bone marrow and 

 the letter of the periosteum, so that the cells forming the two are 

 of a different type. 



Lympho-Sarcoma is the term used to denote primary sar- 

 coma of lymphatic structures. The lympho-sarcomata are com- 

 posed of the same kind of cells, but have a stroma of reticulated 

 lymphadenoid tissue. They are not to be confounded with lymph- 

 adenoma nor with specific inflammatory enlargements involving 

 lymphatic structures. The dividing line between lympho-sarcoma 

 and lymph-adenoma is absolutely vague, as again between lymph- 

 adenoma (Hodgkin's disease) and leukemic lymph-adenoma (lymph- 

 atic leukemia.) Where the growth remains within the capsule 

 of the lymphatic glands then the term lymph-adenoma or "Hodg- 

 kin's disease" may be applied. Where accompanying such glandular 

 overgrowth there is increase in the lymphocytes in the blood, the 

 condition is one of leukemic lymph-adenoma or lymphatic leu- 

 kemia; where the excessive growth of the lymphatic tissue goes 

 on to infiltration and metastases, it is lympho-sarcoma. The lympho- 

 sarcomata are the most malignant of all the sarcomata, and are very 

 infiltrating. On account of their rapidity of growth and profound 

 effect on the general health it has been suggested that they are the 

 product of some very active species of microparasite. Their con- 

 sistence varies from soft to moderately firm with occasional calcar- 

 eous deposits, and the color on section is pinkish or reddish, and 

 they sometimes undergo cystic transformation, containing a red- 

 dish viscous, inodorous liquid. The lymphatics of the Neck and 

 Pubic region are most commonly affected, but any or dl the glands 

 of the body may be involved. These growths are extremely metas- 

 tatic. 



