Granular Venereal Disease of Cows 1 109 



In all the foregoing experiments, the cows received daily wash- 

 ings of the tail, buttocks and perineal regions with 2 % carbolic 

 acid solution, except for a short interval when, in the absence of 

 carbolic acid, lysol or bacillol was used instead. It was found, 

 however, that 2% bacillol or lysol on the skin proved irritant, 

 causing much switching of the tail and stamping with the feet. 

 It was consequently reduced, for external washing, to 1%. 



In the foregoing work we limited ourselves, at the beginning, 

 to the external washings and the introduction of the ointments, 

 powders, solutions, etc., deeply into the vagina. The latter 

 caused much irritation and straining whenever even moderately 

 strong antiseptics were introduced. 



Above we have quoted European authors as using and recom- 

 mending vaginal irrigations with 2-3% bacillol, creolin or lysol 

 solutions, or other antiseptic solutions of similar strength. We 

 were quite unable to use these, because of the straining and irri- 

 tation. But we found that we could use concentrated antiseptic 

 applications in the vulva without serious difficulty. 



European authors do not definitely record the amount of 

 irritation induced by 2% vaginal injections. We do not under- 

 stand how good results could be obtained under such violent irri- 

 tation as we induced with concentrated solutions. In our expe- 

 rience, the irritation retards recovery. After the use of irritant 

 injections, we have found that not only has no progress toward 

 recovery been made while they were used, but, after their aban- 

 donment, the application of otherwise efiicient remedies induces 

 a much more tardy improvement than in cases which have not 

 been touched. Possibly the quoted European authors do not 

 difFerentiate between the vulva and vagina, and introduced the 

 antiseptic solutions into the vulva only. If so, our experience 

 thus far coincides, as we can use similarly concentrated solutions 

 in the vulva. 



Hess, speaking of sterility, intimates that much harm is done 

 by using too concentrated vaginal injections, inducing thickening 

 of the vaginal walls, adhesions and other lesions which may cause 

 insurmountable sterility. 



Based upon our limited experience, we advise daily 

 vaginal irrigations of 0.75% bacillol solution, preceded by 

 disinfection of the tail, perineum and buttocks with a 2% 

 carbolic acid solution and followed by a vulvar irrigation 



