150 VETERINARY OBSTETRICS. 
noticed, the articular synovial membranes are injected, 
thickened and tumified; the synovia, which is very: 
abundant, is suspicious when mixed with flaky clots; 
later it becomes entirely purulent. The articular carti- 
lages are ulcerated; the epiphyses may be necrosed. 
Purulent wasting of the tendons and neighboring 
muscles from peri-articular abscesses; these structures. 
are affected by fatty degeneraticn. Metastatic abscesses. 
in most of the organs and tissues (liver, lungs, brain, 
kidneys, muscles, and subcutaneous connective tissue). 
Finally the heart, liver, kidneys, and muscles have 
undergone fatty degeneration. 
Symptoms.—Enlargement of one or more joints, 
which are hot and tender, general weakness, difficulty 
in moving, or even standing, extreme apathy ; high 
temperature ; pulse and respirations accelerated. Puru- 
lent, and often fetid discharge from the swollen 
umbilical region. Death may take place from coma 
without any alarming premonitory symptoms; at times, 
however, it is preceded by diarrhoea, spasms, and 
paralysis. 
Symptoms may appear which indicate disease of 
other organs (already referred to). 
Treatment.—Curative measures are not at all satis- 
factory, and the greatest hope of success is to be found 
in prophylaxis. 
. The utmost cleanliness should be observed in the 
surroundings of the young animals, the places thoroughly 
disinfected, etc., and the umbilical cord of all young 
animals (especially those most susceptible) should be 
treated antiseptically immediately after birth. 
