GLANDERS. 271 



acute purulent and the chronic inflammatory processes." ' 

 Evidently these differences are only to be explained by 

 differences in the nature of the causes that underlie the 

 several affections. We have studied the characteristics 

 of the bacillus tuberculosis ; we shall now take up the 

 bacillus of glanders and note the striking differences 

 between them. 



The Bacillus of Glanders (bacillus mallei). — In 

 1882 Loffler and Schiitz discovered in the diseased 

 tissues of animals suffering from glanders a bacillus 

 that, when isolated in pure culture and inoculated into 

 susceptible animals, possessed the property of reproduc- 

 ing the disease with all its clinical and pathological 

 manifestations. It is therefore the cause of the disease. 



Fig. 53. 

 Bacillus of glanders {l)a<Allvx mallei). 



It is a short rod, with rounded or slightly pointed 

 ends, that usually takes up the staining somewhat 

 irregularly. (See Fig. 53.) When examined in stained 

 preparations its continuity is marked by alternating 

 darkly and lightly stained areas. It is. usually seen as 

 a single rod, but may occur in pairs, and less frequently 

 in longer filaments. 



1 For a furthet discussion of the pathology and pathogenesis of this disease, 

 see Lehrhuch der pathologisohen Mykologie, by Baumgarten, 1890. 



