154 HEREDITY IN RELATION TO EUGENICS 





tofepist 



Di<f odOODrdc) 



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Fig. 130. — Pedigree of a family showing epistaxis or nosebleed. Affected 

 persons indicated by half shaded symbols. All affected persons arise from 

 an affected ancestor. N, normal. Consorts unknown. Babington, 1865. 



JE 



M 





Fig. 131. — Pedigree of family showing multiple telangiectasis. Affected 

 persons (solid black) from affected parent only. I, 6, had "spots" on face, 

 subject to vomiting and to nosebleed, from which latter he died. II, 5, spots 

 appeared at between 38 and 48 years, epistaxis increased and led to her death. 

 Her daughter, III, 1, is gaining telangiectasis but the younger son at 20 years 

 shows no sign of trouble; II, 6, has red spots that first appeared in her 27th 

 year and are extending. 



ilies there are more than fifty times as many affected males 

 as females. In general as age advances, the severity of the 

 hemorrhages diminishes and finally they cease altogether. 



As in other diseases so in hemophilia special variants ap- 

 pear in particular famihes. Thus among some of the de- 



