Foot-and- Mouth Disease 879 
and signs of the development of the disease, usually 
is short, but may vary from twenty-four hours to twenty 
days. Most cases develop within two or three days 
after exposure. 
Foot-and-mouth disease usually starts with a chill. 
The animal remains by itself, the back is arched, hair 
erect, flanks tucked up, and there is shivering or twitch 
ing of the muscles. A sick animal moves with re- 
luctance, and there is stiffness or marked lameness in 
the gait. A thick, yellowish secretion collects at the 
inner corners of the eyes and about the edges of the 
nostril. The temperature of the animal rises from two 
to five degrees Fahr. Blisters form in the mouth, about 
the feet and on the udder. The blisters vary in size 
from that of a pea to a quarter of a dollar, and are filled 
with a watery fluid. They soon burst, leaving raw 
sores with shreds of tissue hanging about the edges. In 
the mouth the blisters usually form on the lips, tongue, 
cheeks and pad of upper jaw. The animal champs the 
jaws with a smacking noise. There is profuse slavering 
from the mouth. The saliva at first is normal, but later 
becomes thick and ropy. The mouth is often so sore 
that the animal is unable to partake of solid food. The 
blisters about the feet usually occur between the toes of 
cattle, or about the coronet, and often cause severe lame- 
ness. One or all of the feet may be affected. After 
the blisters burst, raw, angry sores result. In some 
eases, the hoof may be shed, or the ulceration may in- 
volve the greater part of the soft structures of the foot. 
So far as known, foot-and-mouth disease was first 
introduced into America in the summer, or early fall, of 
