164 Pyo- Septicemia of Sucklings. 



the aorta. The internal organs present indications of an acute 

 blood infection, the lungs sometimes showing areas of broncho- 

 pneumonia. 



Metastatic abscesses occur with relative frequency in the 

 lungs, where they are always associated with a bronchial 

 catarrh, and sometimes also with a fibrinous or purulent pleu- 

 risy. They may also occur in the liver in the peribronchial, 

 mediastinal and mesenteric lymph glands, in the brain, in the 

 kidneys, etc. Exudative inflammations of the peritoneum, peri- 

 cardium, and of the meninges of the brain, are also frequently 

 associated with the disease. Not infrequently ophthalmitis, 

 with an accumulation of fibrinous and purulent exudate in the 

 anterior chamber of the eye, is present, sometimes also a lique- 

 faction of the crystalline lens. 



Purulent inflammation is found in the majority of cases in 

 the joints of the extremities, most frequently in the hock and 

 knee joints. The more or less swollen joints contain a yellow 

 or reddish semi-liquid, pus-like synovia. The synovial sack 

 appears greatly swollen, bright red and in places ulcerated ; the 

 surface of the cartilage is uneven, its tissues softened, some- 

 times covered with a fibrinous or purulent exudate, which occa- 

 sionally may be traced even into the spongy substance of the 

 bone and into the bone marrow. The pariarticular connective 

 tissue is saturated with serous fluid or with a sero-fibrinous or 

 sero-purulent exudate and in these cases abscesses may also 

 be found, as well as fistulous tracts communicating with the 

 cavity of the joint. The surrounding tissue is always edema- 

 tously infiltrated and the muscles frequently show a fatty degen- 

 eration. The tendon-sheaths may contain a sero-fibrinous or 

 purulent exudate, the tissue of the tendons in such cases show- 

 ing serous infiltration and loosening. Purely metastatic ab- 

 scesses may be present in the subcutaneous as well as in the 

 intra-muscular connective tissue, also in the muscles proper. 



In the peracute cases the changes are less conspicuous, and 

 usually point to general septic infection. The lesions consist 

 of a cloudy swelling of the parenchymatous organs, acute 

 catarrh of the mucous membranes, hyperemia of the spleen, 

 small hemorrhages in the tissue of the serous and mucous mem- 

 branes, sometimes in the small intestines an ulceration of the 

 Peyer's patches, marked acute swelling of the lymph glands, etc. 



In chronic cases (in calves) when the disease has not pro- 

 gressed to an advanced stage, the lungs show signs of broncho- 

 pneumonia, and there exist frequently fibrinous or sero-fibrinous 

 pleurisy and pericarditis. In later stages the broncho-pneu- 

 monic areas show small yellow caseous foci, and still later the 

 lungs contain large firm nodules, which inclose small cavities 

 containing a white or greenish caseous substance. The medias- 

 tinal and peribronchial lymph glands are enlarged and some- 

 times partially caseated. 



