Symptoms. 309 



With the appearance of the eruption the general condition 

 improves, and during the development of the vesicles the 

 patients usually are quite bright. They partake of some food, 

 and also ruminate periodically. Profuse secretion continues 

 to be discharged from the eyes and nose, the respiration may 

 be snuffling owing to the swelling of the skin of the head, and 

 especially of the nostrils. From the corners of the mouth a 

 tenacious, foamy saliva hangs in long strings; the extremities 

 are usually edematously swollen. The animal disseminates a 

 peculiar, sweetish, repulsive odor, which becomes more pro- 

 nounged during the period of suppuration. The general con- 

 dition later becomes worse, but as soon as the suppurative 

 process is concluded, and the drying commences and with the 

 disappearance of the fever the catarrh of the mucous mem- 

 branes also diminishes whereupon the patients usually regain 

 their normal health in a relatively short time, on an average 

 in 3 to 4 days. 



The pox develop in a similar manner on the mucous mem- 

 brane, and simultaneously the eruptions on the skin. Their 

 appearance in the mouth is usually associated with profuse 

 salivation, and when they are present in the pharynx there is 

 difficulty in swallowing, while their appearance on the tongue 

 sometimes causes a marked swelling of this organ. 



' Pox with an Atypical Course. Deviations from the regular 

 course are very frequent. It is probable that the catarrh of the 

 air passages and of the eyes which is sometimes observed in 

 some sheep of an infected herd without other symptoms, and 

 without their developing a severe affection, is the result of a 

 pox infection, which however, owing to the resistance of the 

 animals, was not sufficiently severe to produce an eruption of 

 pox (variola sine exanthemate). 



Frequently it is also observed that the eruptions do not 

 develop into the vesicular stage, but the red and frequently elon- 

 gated nodules remain stationary for a long time, peel off after 

 a few days and disappear (so called abortive or stone pox). 

 These abortive lesions occur sometimes also between well devel- 

 oped vesicles, especially on the parts of the body which are 

 exposed to a greater pressure (variolae compressae, flattened 

 pox), while in other cases the affection is exclusively manifested 

 in an eruption of such nodules. The disease frequently occurs 

 in this mild form among Algerian sheep, in which case small, 

 hard nodules develop only on the head, around the eyes, nasal 

 openings and lips; and in the outbreaks in Germany, in 1905, 

 the manifestations were similar, although the course was quite 

 severe (see p. 303). 



After Ostertag had as the first recognized the disease to be pox, its 

 symptoms were described more accurately by R. Frohner, Kleinpaul, 

 Eber, Eoessler, Noack, Klebba, Haak, and the autopsy findings by 



