372 Strangles. 



submaxillary lymph glands were repeatedly observed in preg- 

 nant mares (Trelut). 



Anatomical Changes. In addition to inflammatory changes 

 in the superficial lymph glands, frequently the size of a fist, 

 autopsy exceptionally reveals abscesses the size of a child's 

 head in the mediastinum and in the vicinity of the bronchi.. 

 They are filled with white, creamy pus containing streptococci, 

 and are frequently divided into several sections by connective 

 tissue walls. By their presence the trachea or the neighboring 

 bronchus may be pushed to one side and may also become 

 compressed. At the same time there may be present a purulent 

 inflammation of the pleura and pericardium. In the lungs there 

 is sometimes only hyperemia and acute edema, at other times 

 a catarrhal pneumonia, or in its tissue various sized abscesses 

 may be imbedded, which are sometimes very numerous. The 

 mucous membrane of the bronchi and trachea, also of the 

 pharynx is always hyperemic, loosened and sprinkled with 

 ecchymoses, and covered with iionsiderable quantities of mucous 

 or purulent secretions. There is frequently a gelatinous in- 

 filtration of aryteno-epiglottic ligaments. 



The lymph glands of the mesentery frequently change to 

 large suppurating masses, when the peritoneum shows marked 

 injection, and the abdominal cavity contains larger or smaller 

 quantities of purulent exudate. Animals which die after long 

 illness are sometimes found to be affected with one or more 

 large abscesses with thick, purulent or caseous contents and 

 adhesions of the neighboring loops of intestines by dense con- 

 nective tissue. Abscesses may also be present in the kidneys, 

 liver, spleen (this is sometimes greatly enlarged- and contains 

 numerous suppurative areas, Lesage; fatal bleeding may take 

 place into the cavity of a large abscess, Berton), pancreas and 

 in the psoas muscle, further in the brain and in the spinal 

 cord, in which they are usually associated with purulent in- 

 flammation of the meninges. They may also be present in the 

 muscles of the neck, and in the axillary region, in the inguinal 

 region, in the tissue surrounding the anus, in the different 

 joints, testicles, the udder, thymus gland, heart muscle, etc. In 

 exceptional cases the mucous membrane of the stomach may be 

 separated from the muscular coat by a flat, diffused layer of 

 pus several millimeters in thickness. 



The autopsy may sometimes reveal degenerative changes 

 in the parenchymatous organs indicating pyemic or septicemic 

 infection. 



Symptoms. After a period of incubation of 4 to 8 days, 

 which possibly may last only 1 to 2 days, especially after 

 colds, exhaustion, etc., the disease commences with symptoms 

 of an acute febrile affection, such as debility, diminished ap- 

 petite, and increased body temperature. Almost at the same 

 time, or not later than after 1 to 2 days, symptoms of acute 



