700 



Glanders. 



edematous tissue. Subsequently, after tliey become adliei'ent 

 to the skin, a small round opening forms and diseliarges a 

 viscous, yellowisli-gray, occasionally reddish pus. By progres- 

 •ion of the destructive process in the borders, rather deep 

 crateriform ulcers form, with grayish-red, easily bleeding 

 l)orders that show torpid granulations and similar but more 

 lardaceous bases and discolored, purulent secretion (see Plate 

 V). They frequently continue to progress in spite of careful 

 treatment, but occnsionally local healing occurs, often with scar 

 form ;d ion. 



In the region of the 

 nodes and ulcers the cen- 

 tripetal Ijmiph vessels fin- 

 ally become enlarged and 

 are then palpable through 

 the skin as slightly paiij- 

 ful or completely insensi- 

 tive tense strands which 

 unite the nodes with tlie 

 ulcers and with the neigli- 

 boring enlarged lymph 

 glands (rosary). Fresh 

 nodes develop in the 

 course of these strands 

 and subsequentlv also ul- 

 cerate (Fig. 119). 



In the meantime the 

 edematous infiltration of 

 the surrounding subcu- 

 taneous connective tissue 

 progresses and spreads 

 over a large area so that 

 finally conspicuous, 

 doughy, painless swellings appear on the lower abdomen, the 

 thorax or on one or more of the extremities. In some instances 

 one or more of the legs become enlarged to such an extent that 

 they resemble logs that are sharply set off at the hoofs 

 (Elephantiasis malleosa), while nodes and ulcers may occur 

 here and there in the tense skin. Enlargements of this character 

 interfere seriously with tjie movements of the limbs, and some- 

 times large nodes, but especially enlarged lymph glands, may be 

 the cause of locomotor distui'bances by exerting pressure on 

 neighboring nerve trunks ; as a rule, however, these disturbances 

 are not serious on account of the painlessness of the condition. 



Fiji. 118. EiiUuficd Subniaxill:iiy Lyiiipli 

 Ciliind in Nasal Glanders. 



Nocard & Leelainelie described a special form of glanders under 

 the name of lymph angioitis reticularis which manifests itself in diffuse 

 swelliiiis; affecting in the course of a few hours one extremity or the 

 lowei' ])()i'tion of the ])ody and is attended with increased heat and pain; 

 after ;i few days the acute symptoms subside somewhat but the swelling 



