702 



Glanders. 



tion of the animals may be re- 

 markably good for a long time. 

 These disturbances manifest 

 themselves in the loss of the nor- 

 mal gloss and smoothness of the 

 haircoat, the elasticity of the 

 skin, gradual emaciation and ex- 

 cessive anemia as indicated by 

 the decided paleness of the visi- 

 ble mucous membranes. 



The body temperature is 

 subject to constant fluctuations. 

 At times the temperature may 

 rapidly approach or exceed 39° 

 to 40° C, but it returns to the 

 normal after a few days or weeks, 

 again undergoing a rise after a 

 few days, weeks, or months (see 

 Fig. 120). These fluctuations are 

 observed much more frequently 

 in work horses than in animals 

 that are permitted to rest much. 



According to Eckert the 

 amount of fibrin in the blood 

 steadily increases toward the 

 termination of the disease while 

 the hemoglobin slightly dimin- 

 ishes, although it shows no fluc- 

 tuations in the course of the dis- 

 ease. Mikrukow observed a re- 

 duction in the number of erythro- 

 cytes and an increase in the leuco- 

 cytes, the proportion being 1 :125 

 near the termination of the dis- 

 ease. The red cells showed no 

 tendency to form rolls, they were 

 paler than normal, greenish in 

 color and of irregular form. 

 Burnett & Pearce also often ob- 

 served leucocytosis. 



In very sick animals heart 

 weakness may develop, resulting 

 in many forms of venous conges- 

 tion (nasal mucous membrane) 

 and being responsible, in part at 

 least, for the edematous swell- 

 ings of the extremities, the abdo- 

 men and the sheath. 



