Symptoms. §59 



intervals of several days, up to several weeks or even 

 longer, exceptionally even after months (Carre & Vallee). 

 They develop without any obvious course, and last from 

 2 to 3 days or even for several days. The rise and also 

 the fall of the temperature always occurs gradually (see Fig. 

 154) . During the febrile rise of temperature the pulse is also 

 more or less increased, sometimes however only very slightly. 

 In_ cases which are not too chronic a moderate increase in pulse 

 exists also in the afebrile periods which becomes well marked 

 even on unimportant external influence, and then appears 

 weaker._ Other febrile symptoms, such as diminished appetite, 

 depression, muscular trembling are absent in very protracted 

 cases, so that if no systematic temperatures are taken, in these 

 cases they can only be recognized in the advanced stage of 

 their development. 



The mucous membranes appear at the beginning either 

 normal in color or slightly ' reddened, in the later stages how- 

 ever they become continuously paler in color, while during the 

 febrile attack, or during a temporary improvement of the con- 

 dition, they may present normal or at least nearly normal color. 

 Hemorrhages are rare in the visible mucous membranes, but 

 they may nevertheless occur. 



The urine usually contains small quantities of albumen 

 in the not very protracted cases, otherwise however it m.ay 

 only appear periodically, especially during the febrile attacks. 

 Not infrequently a periodical fetid diarrhea sets in, and here 

 and there colicky symptoms are observed. 



Edematous swellings of the extremities, or of the lower 

 parts of the rump or the head (on the head especially in pastur- 

 ing animals) are a not infrequent occurrence. 



The blood coagulates only slowly also in this form, so that 

 hemorrhages resulting from external causes can be stopped only 

 with difficulty. The number of red corpuscles diminishes con- 

 siderably, even to 2,000,000 per cubic millimeter of blood 

 (Carre & Vallee). The number of blood corpuscles however 

 varies not a little in accordance with periodical improvement 

 or aggravation, and their diminution may in very protracted 

 cases persist continuously moderate; or on the contrary, after 

 partaking of food and water there may be present a relative 

 increase in red blood corpuscles (see p. 848). Changes in the 

 form of the red blood corpuscles are missed also in this form 

 of the disease in suitably prepared blood specimens. 



The nutrition may be affected from the onset of the disease, 

 or on the contrary in a slowly progressing case it may remain 

 satisfactory for weeks or even for months. Finally however 

 emaciation becomes noticeable even in these cases. It does not 

 progress uniformly, but at times may come to a standstill or 

 the nutritive condition of the patients may improve for a certain 



time. 



In this form the duration of the disease is from one to 



