TDMOES 105 



Do they always occur as pure sarcomata ? 



They do not, but also appear as mixed tumors, as fibro 

 sarcoma, osteo sarcom.a, etc. 



What varieties of sarcomata are recognised ? 



1. The round-celled sarcoma. This is usually soft, vas- 

 cular, fast growing, attains often large size, and gives rise to 

 metastatic deposits in other organs. Its round cells vary in 

 size and are imbedded in a homogeneous intercellular basis 

 substance. On section they exhibit the vascularity and con- 

 sistency of brain matter. 



.Name the subvarieties of round-celled sarcomata. 



(a) The lympho sarcoma. Grows in lymphatic glands. 



(b) The alveolar sarcoma. So called as each cell is 

 enclosed in a separate space or alveolus by the basis 

 substance. 



(c) Melanotic sarcoma. Here the cells and the inter- 

 cellular basis substance is pigmented, due, according 

 to the latest researches, to specific embryonic cells 

 capable of producing pigment. 



2. Spindle-celled sarcoma. It is composed of oat-shaped 

 cells or of very elongated bodies. A subvariety is the mela- 

 notic sarcoma. 



3. Giant-celled sarcoma. It is made up of round and 

 spindle cells and large bone, marrow-like cells with many 

 nuclei. Their consistency is from that of jelly to that of 

 muscle, 



4. Mixed-celled sarcoma. Composed of an admixture- 

 of round, spindle, star-shaped cells. 



5. Endothelioma or angiosarcoma springs from the endo- 

 thelial cells of lymph and blood vessels, which become en- 

 larged and cylindrical. They are very malignant and subject 

 to hemorrhage. 



