110 PBINCIPLES OF VETEBINAEY BUBGEBY 



adheres to the skin and adjacent tissues. In due time it 

 usually implicates the regional lymph glands, and the finale 

 is ulceration of the superjacent parts. Such a carcinomatoiaa 

 ulcer appears, with hard, everted edges, irregular outline and 

 depth, rarely showing granulations, and is usually covered 

 with sloughs. On section the knife creaks as it passes 

 through, the cut surface having a cupped appearance. It is 

 firm and white, very succulent, yielding the so-called cancer 

 juice, a milky iiuid mainly composed of epithelial cells. 



The soft variety on section appears somewhat like hraia 

 substance, both in consistency and looks, for which reason it 

 is also called encephaloid. It is soft, and grows much more 

 rapidly than the scirrhous form. They may form bosselated 

 masses or globular bodies, or are composed of a number of 

 rounded masses. They ulcerate readily, at times exhibiting a 

 nasty, f ungating, easily bleeding, mushroom-like mass termed 

 " fungus hsema todes." 



What secondary changes are carcinomata liable to ? 



Ulceration, cystic degeneration, fatty and myxomatous 

 changes. 



Name the seats of predilection. 



Testicles, mammary glands, parotis, thyroid, prostate 

 gland, kidneys, liver, sudorific and sebaceous glands, etc. 



How is the behavior of carcinomata explained f 



The blood vessels are normal and ramify in the stroma 

 (in the sarcoma they are thin-walled and ramify among the 

 cells). The individual cells of the carcinoma are always of 

 the type of the parent cell; for instance, those originating 

 from the skin are squamous, those from glands are spheroidal, 

 etc. Those carcinomata/ having little fibrous tissue grow 

 fastest, as their blood supply is rich and evenly distributed. 



