I N O 



rfmitting pains in the licad and back, fuccccJcd by tran- 

 sient (hiverings and alternate heats, which continue in a 

 greater or leffer degree till tlie eruption is perfected. 



The inflammation in the arm at this time Ipreads fall, and 

 upon viewing the incifion wiih a good glafs, it appears for 

 the moll part furronnded with an infinite number of fmall 

 puftules, which increafe in fize and extent as the difcafe 

 advances. On the tenth or eleventh day a circular or oval 

 efflorefcence is ufually difcovercd furrounding the incifion, 

 and extending fometimes nearly half round the arm, but 

 more frequently to about the fize of a rtiilling, and, being 

 under the cuticle, is fmootli and not painful. This effloref- 

 cence was alfo regarded as favourable ; it accompanies the 

 eruption, every difagreeable fymptom ceafes, and the pain 

 and ftifFnefs in the axilla go off. 



^Vhen the eruptive fymptoms came on with more fcverity, 

 baron Dimfdale ufed to direft a i-epetition of the lall-men- 

 tioned powder, and on the following morning three or four 

 llools were procured by a laxative draught. 



The baron notices that fonietinio? the ilate of the incifion 

 is fuch for feveral days, that the effects of the inoculation 

 can barely be perceived, the colour about the wound remain- 

 ing pale inftead of changing to red ; the edges of the in- 

 cifion fpread but httle, they remain flat, and are attended 

 neither with itching nor uneafinefs of any kind. Nay, fome- 

 times on the fifth, and even on the fixth day, the alteration 

 is fo little, as to make it doubtful whether the infeftion has 

 taken place. Dimfdale fets down fuch appearances as unfa- 

 vourable, and implying a late and more untoward difeafe. To 

 prevent this, he ufed to dircdl the pewdcr or pill to be taken 

 each night, and in cafe it failed to operate by ftool, or 

 there was the lead difpofition to coftivenefs, an ounce of 

 Glauber's fauce, or a laxative draught, was given in the 

 morning, once or twice, as the cafe might require. The ba- 

 ron believed that thefe meafures forwarded the inflammation, 

 which he always wifhed to fee, as he had conllantly ob- 

 ferved, that an early progrefs on the arm, and an early com- 

 mencement of the eruptive complaints, portended that the 

 diftemper would be mild and favourable ; and on the con- 

 trary, that wlien both were late, the fymptoms proved more 

 irregular and untoward. The patient, initead of being con- 

 fined to his bed or room, when the fymptoms of the erup- 

 tive fever came on, was direfted, as foon a» the purging 

 medicine had operated, to keep abroad in the open air, be 

 it ever fo cold, as much as he could bear, and to drink cold 

 water, if tliirfty, always taking care not to iland iUli while 

 abroad, but to walk about with moderation. 



In certain cafes, notwithflanding baron Dimfdale found 

 the eruptive fymptoms extremely violent, and the patients 

 almoft incapable of motion, and apprehenfive of cold as the 

 greated evil, yet he perfuaded them to rife out of bed and 

 go out of door.s, often fupported by affiftants, and he allowed 

 them to drink as much cold water as tiiey chofe. No finiller 

 accident was the confequence, but, on the contrary, the 

 patients' fpirits were revived, and every fymptom feemed 

 benefited by the method. 



■When any uncommon hinguor haptjened, a bafin of thin 

 broth, or a glafs of wine, was allowed in the day, or fome 

 white-wine whey at bed-time. Indeed, fuch things were 

 allowed at any time to tender, aged, or weakly perfons. 

 ' After the eruption was completed, if occafion required, 

 tliey were indulged in a little well-boiled meat of thelighteft 

 kind, as chicken, veal, or mutton. 



Tlie praftice of baron Dimfdale was certainly, in a great 

 meafure, an imitation of the method purl'ued by Mr, D. 

 Suttuu. 



I N O 



We (liall conclude this article with a fevr neceffary in- 

 ftrudtions and references. 



1 . The a"-e of the perfon to be inoculated for the fmall- 

 pox fliould be as U'tle advanced as poffible ; but (if it can 

 be avoided) not lefs thaa four months. 



2. The matter, when convenient, fliould be taken from a 

 young fubjed wlio has the fmall-pox in a favourable way, 

 and frefii matter fliould have the preference to fuch as is old. 

 It defervcs particular attention, however, that it is chiefly 

 for the fake of avoiding unprofelTional blame that we choofe 

 matter from patients labouring under the difeafe mildly, 

 Cnce experience rather proves, that the lenity or malignity 

 of the fmall-pox depends very little on whether the matter 

 is taken from one patient who has the diftemper favourably, 

 or from another who has it feverely. Nor can we wonder 

 at this fatl, fince the contagion can only be of one fort. 

 Therefore, were a patient much expofed to the cafual 

 fmall-pox, and no matter could be procured from any fub- 

 jeA that had the diflemper mildly, the furgeon fliould recom- 

 mend inocubition with fueh matter as it would be in his 

 power to obtain. 



3. In inoculating, the operator is to make the flighteft 

 punfture, or fcratch, imaginable in the arm over the place 

 where the infcrtion of the deltoid mufcle terminates That 

 part of the lancet wliich is befmeared with the matter, is 

 to be repeatedly rubbed over the wound, and leil the matter 

 be wiped away, it is beft not to pull down the fliirt-flecve 

 till the part is quite dry. Some operators prefer introducing 

 the lancet, armed with the matter, obhquely beneath the 

 cuticle. When this mode is followed, it is proper at the 

 time of withdrawing the lancet to prefs the wound with 

 the finger, fo that the parts in contaft with the matter may- 

 wipe it oft tlie lancet with more certainty. 



The works on the inoculation for the fmall-pox are too 

 numerous to be even mentioned : we would, however, par- 

 ticularly refer to Friend's Hiilory of Medicine. D'Entre- 

 colle's Lcttres Edifiantes et Curieufes. Avicennac Opera. 

 Memoires fur I'Inoculalion par M. de la Condamine. 

 Philofophical Tranfaftions for 1722. Monro on Inocula- 

 tion in Scotland. Holwells Account of the Manner of 

 inoculating in the Eall Indies. Maitland's Account of 

 inoculating the Small-pox. Mead de Variolis ct Morbillis. 

 Kirkpatrick's Analyfis of Inoculation. Some's Small-pox 

 impartially confidered, Sec. Murray's Hift Infitionis 'Va- 

 riolarum in Suecia. Dimfdale's preiVnl Method of inocu- 

 lating for the Small-pox. Jurin's Account of the Succefs 

 of inoculating the Sm<ill-pox in i;2i, &c. and his letter 

 to Dr. Coteiworth. Woodville's Hiitory of the Small- 

 pox, &c. 



For an account of the inoculation f.;r the cow-pox, now 

 fo defervedly preferred to the preceding praftice, fee Cow- 

 po.\ and Vaccix.\tiok. 



A particular defcription of the S.mall-pox will be found 

 under that word. 



IxotxL-VTiON-, Hofpital for. See H0.SPITAL. 



INOFFICIOUS Testament, in Law. See Testa- 

 ment. 



INOM Barley, in Agriculture, a term applied to fuch 

 barley as is fown the fecond crop after the ground has been 

 fallowed, or cleaned from weeds. 



INORDINATE Pkopoiition, is where three magni- 

 tudes being in one rank and three others proportional.to them 

 in another, you compare them in a diff'erent order. 



E.gr. If there be in one rank thefe three numbers, 2, 3, 

 9; and in another rank, thefe other three, S, 24, 36, which 

 are proportional to the precedent, in a different order ; fo 

 that 2 be to 3 as 24 to 36, and 3 to 9 as 8 to 24 ; then call- 

 ing 



