32 CALIFORNIA ACADEMY OF SCIENCES. [ 3 d Ser, 



somes are found separated. Among these types we find 

 those in which one centrosphere encloses one single somo- 

 sphere and one centrosome, while the other centrosphere 

 encloses two distinct centrosomes, as represented in fig. 

 61 ; or we find that one centrosphere encloses one centro- 

 some, and that the other centrosphere contains three centro- 

 somes as in fig. 65; or the division maybe more perfect, 

 and we find three distinct centrospheres, each one with a 

 centrosome. In a word, a very great number of combina- 

 tions may exist, each to be considered as the stage in 

 which the plasmocyte was freed. Whether a further 

 division of the archosome could take place in such a way 

 that each centrosome would form the center of a plasmo- 

 cyte is doubtful, and I must leave this question undecided. 



The Spheres of the Plasmocytes. — As the spheres of the 

 plasmocytes resemble those of the plasmocytoblast so very 

 closely, only a few remarks will suffice to point out the 

 more apparent characteristics. 



The projections of the plasmosphere vary considerably, 

 and I have frequently observed a striking symmetry in their 

 position, in that they occur principally at the poles, thus 

 giving the plasmocyte the appearance of a star, or of a 

 starlike spindle (figs. 46, 73, 74, 51, etc.) 



The hyalosphere is nearly always distinct, narrow, even, 

 and pellucid, giving the impression of being solid, as the 

 other spheres rarely encroach on it. It never becomes 

 coarsely granulated, and if stained with Ehrlich-Biondi it 

 differentiates poorly, while with eosin it sometimes stains 

 faintly pink. I have, however, under favorable conditions 

 observed in this sphere a very fine, regular granulation, 

 consisting of even, rounded globules of exceedingly small 

 size, colorless, and of great transparency. 



The granosphere is, of course, the most prominent of the 

 spheres as regards color, granulation, and size, though all of 

 these vary within certain limits. It is this sphere which 

 takes up foreign substances and digests them, thus exhibiting 

 phagocytosis (fig. 79). In it we find granules of various 

 sizes, staining more or less intensely. Sometimes the grano- 



