22 CALIFORNIA ACADEMY OF SCIENCES. [ 3 d Ser., 



later to this subject, I will only state here that at times it 

 certainly does. When the fusiform corpuscle is finally 

 ejected from the erythrocyte, the cytoplasm is undoubtedly 

 torn from the cell membrane, causing it to assume a star- 

 like appearance, with irregular rays; but later on these 

 rays show forms which can only be explained as the result 

 of amoeboid movements of the plasmosphere. I ascribe 

 amceboid movements to all the spheres except the hyalo- 

 sphere, which appears always dormant as far as regards 

 change of form. 



Hyalosphere. — This sphere extends like an even, narrow, 

 and transparent ring all around the plasmocytoblast. On 

 the three outer sides it is bordered by the plasmosphere, 

 while on the side towards the nucleus it rests against this 

 body. I believe that as a rule the hyalosphere is always 

 found interior to the plasmosphere, though in some instances 

 I have not been able to observe it. In fig. 27, for instance, 

 the hyalosphere is seen below the plasmosphere all around 

 the nucleus, and probably these two spheres always occur to- 

 gether. The hyalosphere appears structureless and hyaline, 

 and is hardly stainable with toluidine. It is always highly 

 refractive. Only by a double stain of eosin and methyl blue 

 "O" has it been possible for me to show with certainty that 

 the hyalosphere is a distinct sphere and not simply a thinner 

 continuation of the plasmosphere. The eosin stains the hy- 

 alosphere pink, while the plasmosphere remains bluish. A 

 characteristic of the hyalosphere is that it is of even size all 

 around, like a transparent highly refractive ring, and that it 

 shows no indication of changing its form by amoeboid move- 

 ments. Until the hyalosphere has closed around the form- 

 ing plasmocyte, this latter, or its counterpart in the plasmo- 

 cytoblast, can only be considered as a fragment of the cell, 

 not yet having resumed that definite form which would char- 

 acterize a finished or fully developed corpuscle. 



The Granosphere. — This sphere is the most prominently 

 noticeable of the various zones which compose the plas- 

 mocytoblasts, especially on account of its darker color, 

 but also by its size. When small the shape is always that 



