62 Royal Society: — 



When twenty grains of carbonate of lithia were taken seven days 

 before the operation, the lens showed not the slightest trace of lithium. 



Twenty grains of carbonate of lithia, taken between six and thirty- 

 six hours before death, showed the faintest indications of lithium in 

 the lens. The cartilage showed lithium very distinctly. 



Ten grains of carbonate of lithia, taken five hours and a half 

 before death, gave only faint traces of lithium in the lens, but the 

 cartilage showed lithium very distinctly. 



5. On the Presence of Lithium in Solid and Liquid Food. 



Potatoes showed traces of lithium once in five trials. 



Apples showed traces of lithium thrice in four trials. 



Carrots showed no lithium in two trials. 



Bread showed traces of lithium thrice in three trials. 



Cabbage „ „ twice in two trials. 



Tea „ „ eight times in ten trials. 



Coffee ,, „ four times in five trials. 



Port wine „ „ six times in six trials. 



Sherry „ „ six times in six trials. 



French wine „ „ four times in four trials. 



Rhine wine „ „ eight times in eight trials. 



Ale ,, „ twice in three trials. 



Porter „ „ twice in three trials. 



Mutton, beef, and sheep's kidney showed no lithium : one kidney 

 had a slight trace. 



Conclusions. 

 1. On the Rate of Passage of Solutions of Lithium into the 

 Textures of Animals. 



Chloride of lithium taken into the stomach in quantities varying 

 from one quarter of a grain to three grains, will pass into all the vas- 

 cular parts of the body, and even into the non-vascular textures, in 

 from one quarter of an hour to five hours and a half. 



2. On the Rate of Passage out of the Textures of Animals. 



Chloride of lithium passes out by the skin as well as by the urine ; 

 and thus the animals can redose themselves with chloride of lithium 

 from the hair and feet, and prevent accurate observations. Hence 

 probably chloride of lithium, in quantities varying from half a grain 

 to three grains, will continue to pass out of the body for thirty-seven, 

 thirty-eight, or thirty-nine days ; and even after thirty- three days, 

 traces may be found in the lens ; but in three or four days no 

 lithium may be detectable in the non-vascular textures. 



3. In man, carbonate of lithia, when taken in five- or ten-grain doses, 

 may appear in the urine in five to ten minutes if the stomach is 

 empty, or twenty minutes if the stomach is full, and may continue to 

 pass out for six, seven, or eight days. 



In two hours and a half, traces may be in the crystalline lens, 

 and in five or seven hours it may be present in every particle of 

 the lens and in the cartilages. In thirty-six hours it may be very 

 evident in the cartilages. And in seven days not the slightest 

 trace may be detectable in the crystalline lens. 



