390 Foreign Literature and Science. 



l a 



To M. Bayle, for the Traite des maladies du cerveau el 

 de ses membranes ; 1 ,500. 



To M. Rochoux, to aid him in printing his Recherches sur 

 les differentes maladies, qu'on appelle jievre jaune ; 1 ,000 

 francs. — Idem. 



30. Sulphate of Quinine. — This valuable compound was 

 first prepared by the authors of its discovery ; but the con- 

 sumption increasing, Pelletier, Robiquet, and Levaillant en- 

 gaged in it in the large way in their chemical manufacto- 

 ries. It would be difficult to ascertain rigorously, the num- 

 ber, origin, and importanqe of the establishments in which 

 the sulphate of quinine is at this moment prepared ; but to 

 give the academy at least a proximate idea, we will here 

 state the numerical results of the work of two fabrics during 

 the year 1826 ; the one is that of one of us, M. Pelletier ; 

 the other, that of M. Levaillant ; this pharmacentical-chem- 

 ist, has obligingly communicated the amount of his registers. 

 Bark, (Quinquina) treated by M. Pelletier on his cwt. 

 own private account, 276 



treated by M. Pelletier in company with 



August Delondre, 460 



by Levaillant for M. Delondre, 420 



by Levaillant for himself and various capi- 

 talists, 437 



Total, 1593 



The various barks made use of were not equally rich in 

 Quinine ; some barks gave 3 gros, 50 grs. of sulphate ; oth- 

 ers, very light, furnished but 2 gros ; but the sulphato of quin- 

 ine was identical ; the mean of the results was 3 gros of 

 sulphate of quinine to the pound of quinquina equal to a 

 _2 s_^ w hich furnishes in 1826 a mass of 59,057 ounces of 

 sulphate of quinine by the two factories alluded to. We 

 are certain of being below the truth, in admitting that the 

 amount manufactured by all the other chemists in France 

 has been equal to the quantity made by one of us, viz. 

 31,000 ounces, corresponding to 80,000 lbs. of quinquina ; 

 we have then 90,000 ounces of sulphate of quinine ; now, 

 in admitting that the mean quantity administered to each 

 of those who have taken it, is 36 grains, in various doses, 

 (and for the most part much less than this is sufficient com- 

 pletely to check the fever,) we shall have in 1826, the 



