FAMILY ACTIXOMYCETACEAE 



915 



growth, with wide, cream-colored edge; 

 white to grayish aerial mycelium gradu- 

 ally covering surface . Reverse of growt h 

 yellowish; no soluble pigment. 



Glucose-asparagine agar: Aerial mj'ce- 

 lium develops slowly. 



Tryptone broth: Growth occurs as 

 small pellets at the base of the flask; 

 later, a thin surface pellicle appears, 

 which consists of a branching mycelium. 

 Black pigment slowly produced. 



Litmus milk: Unchanged. 



Potato: Barnacle-like, brownish, 

 spreading growth; no aerial mycelium. 

 Medium brownish around growth. 



Indole not formed. 



Xo acid from glucose, lactose, maltose, 

 mannitol, sucrose and dulcitol. 



Good growth at 25°C. Slow growth at 

 37°C. 



Distinctive character: Produces an 

 antibiotic substance (proactinomycin) 

 upon synthetic and organic media which 

 is primarily active against various Gram- 

 positive bacteria. 



Source : Isolated as an air contaminant 

 at Oxford, England. 



* Appendix I : The following species 

 probably belong to this genus. Many are 

 incompletel}' described. Some of the 

 species listed here ma}' belong in the 

 genus Streptotnyces. 



Aciinoiiujces albiis ucidus Xeukirch. 

 (Xeukirch, Inaug. Diss., Strassburg, 

 1902, 50; Aclinomyces albus var. acidus 

 Xannizzi, in Pollacci, Tratt. ]\Iicopat. 

 Umana, 4, 1934, 9.) From a case of 

 keratitis. 



Actinomyces avadi Dodge. (Strepto- 

 thrix madurae Koch and Stutzger, Ztschr. 

 f. Hyg., 69, 1911, 17; not Streptothrix 

 madurae Vincent, Ann. Inst. Past., 

 8, 1894, 129; Dodge, Medical Mycology, 



St. Louis, 1935, 729.) From a Madura 

 foot in Egypt, case of Dr. Avad. 



Actinomyces bolognesii-chiurcoi (Vuil- 

 lemin) Dodge. (Malbrachea bolognesii- 

 chiurcoi Vuillemin, in Bolognesi and 

 Chiurco, Archivi di Biol., 1, 1925; Dodge, 

 :\Iedical Mycology, St. Louis, 1935, 766.) 

 From ulcers on the thorax. 



Actinomyces cameli (Mason) Sartory 

 and Bailly. (Streptothrix cameli Mason, 

 Jour. Trop. Med. and Therap., 32, 1919, 

 34; Oospora cameli Sartory, Champ. 

 Paras. Homme et Anim., 1923, 822; 

 Sartory and Baillj', Mycoses Pulmo- 

 naires, 1923, 253.) From pseudotubercu- 

 losis lesions in a camel. 



Actinomyces canis (Rabe) Gasperini. 

 (Discomyces pleuriticus Vachetta, 

 Studi e ricordi clin. ]Milano, 1882; Pleu- 

 romyces canis familiaris Rivolta, Giornali 

 d. Anat. Fisiol. e Patol., 16, 1884, 4; 

 Cladothrix canis Rabe, Berlin, tierarztl. 

 Wochnschr., 1888, 65; Gasperini, Ann. 1st. 

 d'lg. sper. Univ. Roma, 2, 1892, 222; 

 Streptothrix canis and Actinomyces 

 pleuriticus canis familiaris, quoted from 

 Gasperini, Cent. f. Bakt., 15, 1894, 

 684; Leptothrix pleuriticus Piana and 

 Galli-Vallerio, 1896, quoted from Xan- 

 nizzi, in Pollacci, Tratt. Micopat. 

 Lf^mana, 4, 1934, 37; Nocardia canis 

 Chalmers and Christopherson, Ann. 

 Trop. Med. and Parasit., 10, 1916, 255; 

 Oospora canis Sartory, Champ. Paras. 

 Homme et Anim., 1923, 821.) Rabe iso- 

 lated this organism in two cases of phleg- 

 mon and a case of peritonitis in dogs. 



Actinomyces citrocrevieus Xannizzi. 

 (Mycobacteriiun diphtheriae avium Trin- 

 cas, 1907, quoted from Xannizzi, in 

 Pollacci, Tratt. Micopat. Umana, 4, 

 1934, 50; Xannizzi, idem.) Froma disease 

 in birds. 



Actinomyces dassonvillei Brocq- 

 Rousseu. (Brocq-Rousseu, These Sci. 



* The appendix was originally pre])ared by Prof. S. A. Waksman and Prof. A. T. 

 Henrici, May, 1943; it has been developed further by Mrs. Eleanore Heist Clise, 

 Geneva, Xew York, August, 1945. 



