FAMILY BARTONELLACEAE 



1113 



Occur in rings, coccoids of varying 

 size, some very minute, bacillary forms. 



Many of the bacilliform elements show 

 an unstained lens-like swelling, indicat- 

 ing the formation of a ring within the 

 substance of the rod. At the height of 

 the infection most of the organisms are 

 found in the plasma. Whenever an or- 

 ganism comes in contact with a red cell, 

 it stains intensely. 



Pathogenesis : Pathogenic for the gray- 

 backed deer mouse (causing anemia) and 

 for the splenectomized common deer 

 mouse. Not pathogenic for splenectom- 

 ized white mice. 



Habitat : Blood of the gray-backed deer 

 mouse (Perotnyscus maniculatus gra- 

 cilis). 



5. Eperythrozoon dispar Bruynoghe 

 and Vassiliadis. (Ann. de Parasitol., 7, 

 1929, 353.) 



Resembles Eperythrozoon coccoides in 

 staining, distribution on the erythro- 

 cytes and also in appearance except that 

 circular disks with solid staining centers 

 may greatly outnumber the ring forms. 

 Found on the red blood cells and in the 

 plasma. Size range that of Eperythro- 

 zoon coccoides, also some larger ring forms. 



Cultivation: Not successful. 



Immunology: Infection is followed by 

 premunition and latent infection is made 

 manifest by splenectomy. Splenectom- 

 ized rabbits premunized against E. coc- 

 coides do not react to inoculation with 

 E. dispar; if the latter is injected first, 

 they do not react to E. coccoides. 



Infectivity : Infective for the European 

 vole {Arvicola[Microtus] arvalis), the 

 American vole (Microtus pennsylvanicus 

 pennsylvanicus) , the dwarf mouse {Mus 

 minutus), the rabbit, and Mus aconiys. 



Not infective for albino rats or albino 

 mice. 



Source: Blood of infected animals. 



Appendix: 1) Species incompletely 

 studied, Eperythrozoon spp. and Epery- 

 ihrozoon-like structures (Weinman, 

 Trans. Amer. Philosoph. Soc, N. S. S3, 

 pt. 3, 1944,320). 



Eperythrozoon noguchii Lwoff and Vau- 

 cel. (Bull. Soc. path, exot., 26, 1933, 

 397.) Probably not a valid species. 



Eperythrozoon perekropovi Yakimoff. 

 (Arch. f. Protistenk., 73, 1931, 271.) 

 Classification in genus Eperythrozoon 

 questionable. 



Bartonella wenyoni Nieschulz. 



(Ztschr. f. Infektionskr., 53, 1938, 178.) 

 Probably identical with Eperythrozoon 

 wenyoni. If valid, Haemohartonella 

 wenyoni. 



Possible human infection (Schiiffner, 

 Nederl. tijdschr. v. geneesk., 73, 1939, 

 3778). 



2) Animals infected with parasites 

 which are definitely eperythrozoon-like 

 but of uncertain specificity or which are 

 eperythrozoon-like in some features but 

 which can not be definitely classified 

 generically : 



Jerboa sp. Kikuth. (Cent. f. Bakt., I 

 Abt., Orig., 123, 1931, 356.) 



Arvicola arvalis Zuelzer. (Zuelzer, 

 Cent. f. Bakt., I Abt., Orig., 102, 1927, 

 449; Kikuth, Ergebn. Hyg. Bakt., Im- 

 munitatsforsch. u. Exper. therap., 13, 

 1932, 559.) 



Rattus rattns Schwctz. (Ann. Soc. 

 beige de med. trop., U, 1934, 277.) 



Sciurus vulgaris Nauck. (Arch. f. 

 Schiffs- u. Trop. -Hyg., 31, 1927, 322.) 



Leptodactylus pentadactylus Carini. 

 (Compt. rend. Soc. Biol., Paris, 103, 

 1930, 1312.) 



