FAMILY CHLA MYDOZOACEA E 



1119 



Filterabiiity : Filters through Berke- 

 feld N and Maudler 6, 7 and 9 filters. 



Cultivation : In the yolk sac of the 

 chicken embryo. 



Immunological aspects : Indistinguish- 

 able from other miyagawanellae by com- 

 plement fixation tests with yolk sac an- 

 tigens. Partly distinguished from Mi- 

 yagawanella psittaci and M. ornithosis 

 by active immunization in mice and 

 guinea pigs. 



Pathogenicity : Pathogenic for man, 

 guinea pigs, cotton rats, mice and chicken 

 embryos. Slightly pathogenic for white 

 rats, golden hamsters and deer mice. 

 Macacus rhesus monkeys, rabbits, musk- 

 rats and nutria are unaffected. Causes a 

 highly fatal pneumonitis and septicemia 

 in man. 



Tissue tropisms: Causes a septicemia. 

 In man this species shows predilection 

 for the respiratory tract. In laboratory 

 rodents it is infective by the intranasal, 

 intraperitoneal, intracerebral, intra- 

 muscular and subcutaneous routes. 



Chemotherapy : As for Miyagawanella 

 ornithosis. 



Source: Sputum and organs of in- 

 fected persons. 



Habitat : The etiological agent of 

 Louisiana pneumonia (Olson and Larson, 

 U. S. Pub. Health Repts., 59, 1944, 1373), 

 so-called Borg strain. 



8. Miyagawanella illinii Rake, spec. 



nor. Xamed for the State of Illinois. 



Coccoid bodies : As for Miyagaicanella 

 lymphogran ulomatis . 



Filterabiiity : Passes through Berke- 

 feld N or W filters. 



Cultivation : In the yolk sac of chicken 

 embryo. 



Immunological aspects: Distinguished 

 from other miyagawanellae by neutrali- 

 zation tests in mice with chicken anti- 

 sera and partly from Miijagaivanella psit- 

 taci, M. ornithosis and M. pneumonia by 

 active inununization in mice. 



Pathogenicity : Pathogenic for man and 

 white mice . Causes a highly fatal pneu- 

 monitis in man. 



Tissue tropisms : Infective in mice by 

 the intranasal, inti-aperitoneal, intra- 

 cerebral and subcutaneous routes. 



Source : Lungs of infected persons. 



Habitat : The etiological agent called 

 the Illinois virus (Zichis and Shaugh- 

 nessy, Science, 102, 1945, 301). 



Genus III. Colesiota Rake, gen. nov. 



{Rickettsia Coles, 17th Rept. Direct. Vet. Serv. and An. Ind. Un. South Africa, 

 1931, 175.) Named for Prof. Coles who first studied these organisms. 



Pleomorphic cells which may be coccoid, triangular, rod-shaped or in the form of 

 rings. Gram-negative. Intracytoplasmic habitat. 



The type species is Colesiota conjunctivae (Coles) Rake. 



1. Colesiota conjunctivae (Coles) 

 Rake, cotnb. nor. {Rickettsia conjuncti- 

 vae Coles, 17th Rept. Direct. Vet. Serv. 

 and An. Ind. Un. South Africa, 1931, 17.5; 

 Chlamydozoon conjunclirac Moshkovsky, 

 Uspeklii Souremennoi Biologii, 19, 1945, 

 19.) From M. L. conjunctira. the con- 

 junctiva. 



Pleomorphic bodies : Average diameter 

 600 to 950 millimicrons. May be solid 

 and coccoid, rod-shaped, or triangular, 

 or in form of open rings or horse-shoes. 



No chains. Masses fi-equent. No cap- 

 sule. Stains with ordinary aniline dyes 

 but less intense]}' than bacteria. Gram- 

 negative. Non-motile. 



Cultivation : Has never been culti- 

 vated. 



Immunological aspects: Unknown. 



Pathogenicit}^ : Pathogenic for sheep, 

 cattle and goats. Causes acute con- 

 junctivitis and keratitis. 



Tissue tropisms : Affects only the con- 

 junctiva and cornea. 



