FAMILY PHAGACEAE 



1137 



and Chalmers, Shigella dyscnteriae Cas- 

 tellani and Chalmers, Shigella gallinarinn 

 Weldin, Salmonella typhosa White. 



Induced disease : Small plaques with 

 sharp edges, or moderately large plaques 

 with characteristic halo. 



Immunological relationships : Member 

 of Resistance Group B ; host individuals 

 that have acquired resistance to this bac- 

 teriophage are resistant to lines 18, 28, 

 31, 34, and 38, but susceptible to Sal- 

 monella enteritidis bacteriophages 1, 20, 

 and 11, as well as to other strains of Re- 

 sistance Groups A, C, and D. 



Literature: Burnet, Jour. Path, and 

 Bact., 3£, 1929, 15-42. 



22. Phagus tertius H. {loc. cit., 154). 

 From Latin tertius, third, in reference to 

 the third Resistance Group of Salmonella 

 enteritidis bacteriophages, Group C, typi- 

 fied by this bacteriophage. 



Common names : Salmonella enteritidis 

 bacteriophage 20, 25, 32, 35; Group C 

 bacteriophages. 



Hosts : Salmonella enteritidis Castellani 

 and Chalmers, S. gallinarum Bergcy et 

 al., Shigella dysenteriae Castellani and 

 Chalmers. 



Induced disease : Plaques of small size, 

 with sharp edges. 



Immunological relationships : Member 

 of Resistance Group C. Host individuals 

 that have acquired resistance to this bac- 

 teriophage are resistant to lines 25, 35, 

 and 32, but susceptible to Salmonella 

 enteritidis bacteriophages of Resistance 

 Groups A, B, and D. 



Literature: Burnet, Jour. Path, and 

 Bact., 3^, 1929,15-42. 



23. Phagus dubius H. (loc. cit., 155). 

 From Latin dubius, doubtful, in reference 

 to uncertainty of distinction between 

 Resistance Groups C and D. 



Common names : Salmonella enteritidis 

 bacteriophage 11, 13; Group D bacterio- 

 phages . 



Hosts : Salmonella enteritidis Castellani 

 and Chalmers, Shigella dysenteriae Cas- 



tellani and Chalmers, Shigella gallinarum 

 Weldin. 



Induced disease : Very large plaques, 

 up to 8 mm in diameter on 1.2 per cent 

 agar. 



Immunological relationships : Member 

 of Resistance Group D. Host individ- 

 uals that have acquired resistance to this 

 bacteriophage are resistant to line 13, but 

 susceptible to Salmonella enteritidis bac- 

 teriophages of Resistance Groups A, B, 

 and C. 



Literature: Burnet, Jour. Path, and 

 Bact., 32, 1929, 15-42. 



24. Phagus indicens spec. not'. From 

 Latin indicere, to disclose or indicate, in 

 reference to diagnostic use of this bac- 

 teriophage in identifying V forms of the 

 typhoid bacillus. 



Common name : Phage Q151. 



Host: Salmonella typhosa White ( = 

 Bacillus typhosus Zopf). 



Insusceptible species : W forms of the 

 typhoid organism and various Salmonella 

 species. 



Geographical distribution : Canada. 



Induced disease : In Salmonella typhosa, 

 small plaque formation (lysis) and com- 

 plete inhibition of growth in cultures of 

 the V form (bearing Vi antigen ; resisting 

 O agglutination) and no lysis or restrain- 

 ing effect on growth of the W form (lack- 

 ing Vi antigen; agglutinated by O anti- 

 serum). In the presence of the virus, 

 mixed cultures are ciuickly transformed 

 since only W variants can increase . Pure 

 V cultures can be identified by the test 

 for their complete inhibition; this in- 

 hibition is regularly followed by second- 

 ary growth representing the pure W form 

 of the host, a readily formed variant. 



Filterability : Passes Seitz EK filter. 



Other properties : Filtrates active in 

 dilutions to 10"^ or lO"". 



Literature: Craigie, Jour. Bact., 31, 

 1936, 56 (Abst.); Craigie and Brandon, 

 Jour. Path, and Bact., 43, 1936, 233-248, 

 249-260. 



