123G 



MANUAL OF DETERMINATIVE BACTERIOLOGY 



f. Hyg., 115, 1933, 342-353 ; Be dsoii, Brit. 

 Jour. Exp. Path., 12, 1931, 254-260; 

 Bedson and Bland, ibid., 9, 1928, 174-178; 

 Blanc and Caminopetros, Compt. rend. 

 Soc. Biol., Paris, 84, 1921, 859-860; Boak 

 et al., Jour. Exp. Med., 71, 1940, 169-173; 

 Brain, Brit. Jour. Exp. Path., IS, 1932, 

 166-171 ; Buggs and Green, Jour. Inf. Dis., 

 58, 1936, 98-104; Burnet and Lush, Jour. 

 Path, and Bact., 48, 1939, 275-286; 49, 

 1939, 241-259; Lancet, 236, 1939 (1), 

 629-631; Burnet et al., Austral. Jour. 

 Exp. Biol, and Med. Sci., 17, 1939, 35-40; 

 Dawson, Am. Jour. Path., 9, 1933, 1-6; 

 Elford et al.. Jour. Path, and Bact., 86, 

 1933, 49-54; Findlay and MacCallum, 

 Lancet, 238, 1940 {1), 259-261 ; Fischl and 

 Schaefer, Klin. Wochnschr., 8, 1929, 

 2139-2143; Flexner, Jour. Gen. Physiol., 

 8, 1927, 713-726; Jour. Exp. Med., 47, 

 1928, 9-36; Friedenwald, Arch. Ophthal- 

 mol., 52, 1923, 105-131; Goodpasture, 

 Medicine, 8, 1929, 223-243; Goodpasture 

 and Teague, Jour. Med. Res., 44, 1923, 

 121-138; Gunderson, Arch. OpthalmoL, 

 15, 1936, 225-249 ; Holden, Jour. Lif. Dis., 

 50, 1932, 218-236; Keddie and Epstein, 

 Jour. Am. Med. Assoc, 117, 1941, 1327- 

 1330; Levaditi and Lepine, Compt. rend. 

 Acad. Sci., Paris, 189, 1929, 66-68; Leva- 

 diti and Nicolau, Compt. rend. Soc. Biol., 

 Paris, 90, 1924, 1372-1375; Long, Jour. 

 Clin. Investigation, 12, 1933, 1119-1125; 

 Magrassi, Boll. 1st. Sieroterap. Milanese, 

 14, 1935, 773-790; McKinley, Proc. Soc. 

 Exp. Biol, and Med., 26, 1928, 21-22; 

 Naegeli and Zurukzoglu, Cent. f. Bakt. 

 I Abt., Orig., 135, 1935, 297-299 ; Nicolau 

 and Kopciowska, Ann. Inst. Pasteur, 60, 

 1938, 401-431 ; Parker and Nye, Am. Jour. 

 Path., 1, 1925, 337-340; Perdrau, Proc. 

 Roy. Soc. London, Ser. B, 109, 1931, 304- 

 308; Jour. Path, and Bact., 47, 1938, 447- 

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 Soc. Biol., Paris, 94, 1926, 734-736; 1064- 

 1066; 95, 1926, 1542-1545; 96, 1927, 404- 

 406; 1126-1128; 97, 1927, 109-111; Sabin, 

 Brit. Jour. Exp. Path., 15, 1934, 372-380; 

 Schultz and Hoyt, Jour. Immunol., 15, 

 1928, 411-419; Shaffer and Enders, ibid., 

 37, 1939, 383-411; Simon, International 



Clinics, Series 37, 3, 1927, 123-128; Smith 

 et al.. Am. Jour, Path., 17, 1941, 55-68 

 Warren et al.. Jour. Exp. Med., 71, 1940 

 155-168; Weyer, Proc. Soc. Exp. Biol 

 and Med., 30, 1932, 309-313; Zinsser 

 Jour. Exp. Med., 49, 1929, 661-670 

 Zinsser and Seastone, Jour. Immunol. 

 18, 1930, 1-9; Zurukzoglu and Hruszek 

 Cent. f. Bakt. I Abt., Orig., 128, 1933 

 1-12. 



2. Scelus suillum spec. nov. From 

 Latin siiillus, pertaining to swine. 



Common names: Pseudorabies virus, 

 mad-itch virus. 



Hosts : Domestic cattle, swine, dog, cat, 

 horse, sheep. Experimentally, also rab- 

 bit, guinea pig, white rat, white mouse, 

 gray field mouse, duck, chicken, chick 

 embryo; Macaca mvlaita (Zimmermann), 

 rhesus monkey. 



Geographical distribution: France, 

 Germany, Hungary, Holland, Denmark, 

 Switzerland, Siberia, Brazil, United 

 States. 



Induced disease : In cattle, licking of 

 affected area, usually somewhere on hind- 

 quarters, sudden decrease in milk pro- 

 duction in dairy animals, violent rubbing, 

 biting, and gnawing of lesion; swelling 

 and discoloration of affected parts with 

 oozing of serosanguineous fluid ; grinding 

 of teeth and excessive salivation in some 

 individuals; death, preceded by clonic 

 convulsions, violent tossing of head, and 

 shallow respiration, usually 36 to 48 hours 

 after onset. In pig, mild but highly con- 

 tagious disease ; slight nerve-cell degen- 

 eration, predominance of vascular and 

 interstitial lesions. 



Transmission : By contact in swine, not 

 in cattle. By feeding in cats, brown rats, 

 and swine. 



Serological relationships : Cross neu- 

 tralization between constituent strains. 

 Anti-herpes sera protect in some cases 

 against small, but constantly infective, 

 doses of pseudorabies virus. 



Literature: Aujeszky, Cent. f. Bakt. 

 I Abt., Orig., 32, 1902, 353-357; F. B. 

 Bang, Jour. Exp. Med., 76, 1942, 263-270; 



