1242 



MANUAL OF DETERMINATIVE BACTERIOLOGY 



31, 1905, 1598-1599; Lipschiitz, Arch. 

 Dermat. u. Syph., 107, 1911, 387-396; in 

 Kolle, Kraus and Uhlenhuth, Handbuch 

 der Pathogenen Mikroorganismen, 8, 

 1930, 1031-1040; Van Rooyen, Jour. Path, 

 and Pact., 46, 1938, 425-436; 49, 1939, 

 345-349; Wile and Kingery, Jour. Cutan. 

 Dis., 37, 1919, 431-446. 



3. Molitor bovis spec. nov. From Latin 

 bos, cow. 



Common name : Cattle-wart virus. 



Host: BOV IDAS— Bos taurus L., do- 

 mestic cattle. 



Geographical distribution: United 

 States. 



Induced disease: In cattle, especially 

 about head, neck, and shoulders in young 

 animals, on udders in cows, affected skin 

 thickened at first, then rough, nodular; 

 warts sometimes become large and pendu- 

 lous, adversely affecting growth of host ; 

 they sometimes become cauliflower-like 

 tumors several inches in diameter; spon- 

 taneous regression is not infrequent. 

 Hides from affected animals are reduced 

 in value. 



Transmission : Pelieved to be through 

 injuries to skin when the injured part 

 comes in contact with warty animals or 

 with rubbing posts, chutes, fences, build- 

 ings, or other structures with which 

 affected animals have come in contact pre- 

 viously. Experimentally, by skin inocu- 

 lations, especially in animals under 1 ,vear 

 of age. 



Filterability : Passes Perkefeld N filter. 



Literature: Creech, Jour. Agr. Res., 

 39, 1929, 723-737; U. S. Dept. Agr., Leaf- 

 let 75, 1931, 1-4. 



4. Molitor buccalis spec. nov. From 

 Latin bucca, cheek. 



Common name : Canine oral-papillo- 

 rnatosis virus. 



Host : CAN IDA E — Can is fa m il iar is 

 L., dog. 



Insusceptible species: Cat, rabbit, 

 guinea pig, rat, mouse; Macaca mulatta 

 (Zimmermann), rhesus monkey. 



Induced disease : In young dog, experi- 

 mentally, about 1 month after inocula- 

 tion of buccal membrane by scarification, 



pale, smooth elevations, becoming gradu- 

 ally^ more conspicuous and roughened ; 

 finally a mass of closely packed papillae 

 is formed. Regression with subsequent 

 immunity is frequent ; no scars are left 

 on regression. Secondary warts often 

 appear in other parts of the mouth 4 to 6 

 weeks after primarj^ warts have first been 

 observed. 



Transmission : Experimentally by skin 

 scarification. 



Serological relationships : Not inhibited 

 by antiserum effective against common- 

 wart virus of man. 



Thermal inactivation : At some tem- 

 perature between 45 and 58° C in 1 hour. 



Filterability : Passes Berkefeld N filter. 



Other properties : Viable after freezing 

 and drying, if stored dry in icebox, at 

 least 63 days ; in storage in equal parts of 

 glycerine and 0.9 per cent NaCl solution 

 at least 64 days. 



Literature : DeMonbreun and Good- 

 pasture, Am. Jour. Path., 8, 1932, 43-56; 

 M'Fadyean and Hobday, Jour. Comp. 

 Path, and Therap., 11, 1898, 341-344; 

 Penberthy, ibid., 11, 1898, 363-365. 



5. Molitor tumoris spec. nov. From 

 Latin tumor, swelling. 



Common names : Fowl-sarcoma virus, 

 Rous chicken-sarcoma virus. 



Hosts : P HAS I AN I DAE— Callus gal- 

 lus (L.), chicken. Experimentally, also 

 pheasant (serial transfer difficult) and 

 duck (by cell transfer only but filtrates 

 from duck infect injected chicken). 



Insusceptible species : Turkey, guinea 

 fowl (both immune to filtrates but ca- 

 pable of supporting tumor line if alterna- 

 ted in a series with common fowl hosts) ; 

 geese . 



Induced disease : In hen, originally 

 found in an adult, pure-bred hen of 

 Barred Plymouth Rock variety. Experi- 

 mentally transmitted, a circumscribed 

 nodule soon becomes evident at site of 

 implantation ; later this becomes necrotic 

 or cystic at its center ; as growth enlarges, 

 host becomes emaciated, cold, somnolent, 

 and finally dies; discrete metastases are 

 often found in lungs, heart, and liver. 

 Parent cell of sarcoma is claimed to be 



