!\. UUFACEJE. zoo 



above. It, therefore, demands an especial notice of the medi- 

 cal profession. 



" Six drachms of the tincture or twelve ounces of the decoc- 

 tion of T. aculeata are equal to one bottle of Warburg's 

 tincture ; and if either of them is used in two doses during 

 the presence of simple continued fever or a paroxysm of ague, 

 it produces the same good effect as the latter drug (Warburg's 

 tincture), namely, a copious perspiration and relief of the 

 febrile condition ; and, again, if the tincture or decoction is 

 repeated in the same dose during the interval of ague, every 

 fourth or fifth hour, for two or three days, it prevents the 

 return of paroxysm as successfully as very large doses of 

 quinine. To render the cure more perfect and complete, the 

 tincture or decoction should be continued in smaller doses for 

 four of five days more. The beneficial influence of the tincture 

 or decoction of T, aculeata in remittent fever is precisely the 

 same, and the only difference is that it sometimes relieves the 

 exacerbation and checks its return at once; and at others, it 

 first converts the remittent into intermittent fever and then 

 cures the latter in the same way as explained above. Out of 

 the many severe and very obstinate cases of malarious, jungle, 

 and other fevers, which yielded to this drug, there were several 

 in which quinine with arsenic was first tried and failed. As the 

 dose of the tincture of T. aculeata is much smaller than that of 

 its decoction, and as it can also be prepared and kept always ready 

 for use, it is preferable to the latter; but there is no difference 

 whatever between the medical properties of both preparations. 



" The root-bark of T. aculeata is not only much cheaper 

 than quinine and Warburg's tincture, but is also one of the 

 cheapest drugs in Southern India, its price being only about 

 2 annas per pound. In addition to this, its advantages over 

 quinine are that it, unlike the latter, can be freely and success- 

 fully administered in tbe absence as well as in the presence 

 of fever ; and that, however long and frequently it may be em- 

 ployed, it never produces ringing in the ears, deafness and 

 some other disagreeable symptoms which are so commonly 

 observed in the use of quinine. 



